SCTR-AS1

Summary

SCTR-AS1 (SCTR antisense RNA 1, HGNC:40516) is a long non-coding RNA gene on chromosome 2q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40516
Approved symbol	SCTR-AS1
Name	SCTR antisense RNA 1
Location	2q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231013
Ensembl biotype	lncRNA
Entrez	107105282
RNAcentral	URS0000BC45A6 — lncRNA, 2074 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000413602, ENST00000457436, ENST00000657643, ENST00000719694

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413602 — 2 exons

Exon	Start	End
ENSE00001622135	119476448	119476958
ENSE00001710500	119485839	119487346

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 89.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0286 / max 23.5318, expressed in 7 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
22274	0.0221	7
202366	0.0065	3

Top tissues by expression

202 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	89.00	gold quality
pancreas	UBERON:0001264	87.17	gold quality
islet of Langerhans	UBERON:0000006	86.18	gold quality
metanephros cortex	UBERON:0010533	77.05	gold quality
adult mammalian kidney	UBERON:0000082	71.41	gold quality
cortex of kidney	UBERON:0001225	67.79	gold quality
kidney	UBERON:0002113	66.47	gold quality
metanephros	UBERON:0000081	66.24	gold quality
renal medulla	UBERON:0000362	63.99	gold quality
apex of heart	UBERON:0002098	61.30	gold quality
heart left ventricle	UBERON:0002084	60.64	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.61	gold quality
prefrontal cortex	UBERON:0000451	60.59	gold quality
ventricular zone	UBERON:0003053	60.11	gold quality
cardiac ventricle	UBERON:0002082	60.01	gold quality
cortical plate	UBERON:0005343	59.69	silver quality
right atrium auricular region	UBERON:0006631	59.25	gold quality
right lung	UBERON:0002167	58.80	gold quality
cardiac atrium	UBERON:0002081	58.73	gold quality
muscle of leg	UBERON:0001383	58.51	gold quality
heart	UBERON:0000948	58.33	gold quality
right frontal lobe	UBERON:0002810	58.33	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.38	gold quality
ganglionic eminence	UBERON:0004023	56.99	silver quality
gastrocnemius	UBERON:0001388	56.85	gold quality
frontal cortex	UBERON:0001870	55.86	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	55.76	gold quality
duodenum	UBERON:0002114	55.45	gold quality
biceps brachii	UBERON:0001507	55.28	silver quality
right lobe of liver	UBERON:0001114	55.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.01

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.