SCUBE1-AS1

Summary

SCUBE1-AS1 (SCUBE1 antisense RNA 1, HGNC:40635) is a long non-coding RNA gene on chromosome 22q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40635
Approved symbol	SCUBE1-AS1
Name	SCUBE1 antisense RNA 1
Location	22q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000203527
Ensembl biotype	lncRNA
Entrez	101927447
RNAcentral	URS0000A766D4 — lncRNA, 1994 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000458463

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458463 — 2 exons

Exon	Start	End
ENSE00001630328	43275955	43276011
ENSE00001631746	43281937	43283830

Expression profiles

Bgee: expression breadth broad, 18 present calls, max score 70.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0677 / max 8.4388, expressed in 31 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
192604	0.0677	31

Top tissues by expression

166 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	70.75	silver quality
sural nerve	UBERON:0015488	64.06	gold quality
cortical plate	UBERON:0005343	61.78	silver quality
ganglionic eminence	UBERON:0004023	56.31	silver quality
buccal mucosa cell	CL:0002336	50.57	gold quality
spleen	UBERON:0002106	48.46	gold quality
gastrocnemius	UBERON:0001388	47.56	silver quality
right ovary	UBERON:0002118	46.55	gold quality
left ovary	UBERON:0002119	44.86	gold quality
ovary	UBERON:0000992	44.40	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
lower esophagus muscularis layer	UBERON:0035833	43.20	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.15	silver quality
amniotic fluid	UBERON:0000173	43.05	gold quality
lymph node	UBERON:0000029	42.89	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
esophagus	UBERON:0001043	42.49	silver quality
adult mammalian kidney	UBERON:0000082	42.40	gold quality
blood	UBERON:0000178	42.18	gold quality
tibial nerve	UBERON:0001323	41.82	silver quality
stomach	UBERON:0000945	41.79	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
adrenal gland	UBERON:0002369	41.21	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.