SCUBE1-AS2

Summary

SCUBE1-AS2 (SCUBE1 antisense RNA 2, HGNC:40633) is a long non-coding RNA gene on chromosome 22q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40633
Approved symbol	SCUBE1-AS2
Name	SCUBE1 antisense RNA 2
Location	22q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236272
Ensembl biotype	lncRNA
Entrez	105373051
RNAcentral	URS0000400349 — lncRNA, 531 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000420269

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420269 — 2 exons

Exon	Start	End
ENSE00001592948	43212674	43212697
ENSE00001732486	43213155	43213661

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 84.18.

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.18	silver quality
right testis	UBERON:0004534	80.39	gold quality
left testis	UBERON:0004533	79.02	gold quality
testis	UBERON:0000473	78.15	gold quality
right uterine tube	UBERON:0001302	71.78	gold quality
left adrenal gland cortex	UBERON:0035825	67.74	gold quality
right adrenal gland cortex	UBERON:0035827	67.00	gold quality
mucosa of stomach	UBERON:0001199	66.94	gold quality
sural nerve	UBERON:0015488	66.83	gold quality
left adrenal gland	UBERON:0001234	66.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.49	gold quality
adrenal gland	UBERON:0002369	65.25	gold quality
right adrenal gland	UBERON:0001233	64.59	gold quality
cortical plate	UBERON:0005343	64.49	gold quality
ganglionic eminence	UBERON:0004023	64.16	gold quality
left ovary	UBERON:0002119	63.11	gold quality
ovary	UBERON:0000992	62.34	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.13	gold quality
right ovary	UBERON:0002118	61.11	gold quality
tibial nerve	UBERON:0001323	60.72	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.07	gold quality
lower esophagus	UBERON:0013473	60.01	gold quality
adult mammalian kidney	UBERON:0000082	59.50	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	58.83	gold quality
kidney	UBERON:0002113	58.47	gold quality
endocervix	UBERON:0000458	58.01	gold quality
prefrontal cortex	UBERON:0000451	57.01	gold quality
esophagus	UBERON:0001043	56.06	gold quality
liver	UBERON:0002107	55.84	gold quality
right lung	UBERON:0002167	55.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.