SEC23A-AS1

Summary

SEC23A-AS1 (SEC23A antisense RNA 1, HGNC:53213) is a long non-coding RNA gene on chromosome 14q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53213
Approved symbol	SEC23A-AS1
Name	SEC23A antisense RNA 1
Location	14q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258651
Ensembl biotype	lncRNA
Entrez	105370458
RNAcentral	URS0000109ABA — lncRNA, 500 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000557350, ENST00000760424

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000557350 — 2 exons

Exon	Start	End
ENSE00002472340	39103545	39103812
ENSE00002517896	39103140	39103371

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 86.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2311 / max 7.0737, expressed in 93 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
139340	0.2311	93

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.52	gold quality
skeletal muscle tissue	UBERON:0001134	66.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.82	gold quality
ganglionic eminence	UBERON:0004023	63.95	gold quality
cortical plate	UBERON:0005343	63.75	gold quality
islet of Langerhans	UBERON:0000006	61.30	gold quality
prefrontal cortex	UBERON:0000451	60.70	gold quality
duodenum	UBERON:0002114	60.27	gold quality
lymph node	UBERON:0000029	59.78	gold quality
monocyte	CL:0000576	59.59	gold quality
superior frontal gyrus	UBERON:0002661	59.53	gold quality
rectum	UBERON:0001052	58.47	gold quality
stromal cell of endometrium	CL:0002255	58.42	gold quality
primary visual cortex	UBERON:0002436	58.27	gold quality
gall bladder	UBERON:0002110	58.12	gold quality
mucosa of stomach	UBERON:0001199	58.05	gold quality
mucosa of transverse colon	UBERON:0004991	57.87	gold quality
bone marrow	UBERON:0002371	57.52	gold quality
left coronary artery	UBERON:0001626	57.28	gold quality
muscle of leg	UBERON:0001383	57.09	gold quality
smooth muscle tissue	UBERON:0001135	57.04	gold quality
vermiform appendix	UBERON:0001154	56.56	gold quality
popliteal artery	UBERON:0002250	56.52	gold quality
tibial artery	UBERON:0007610	56.50	gold quality
right coronary artery	UBERON:0001625	56.47	gold quality
gastrocnemius	UBERON:0001388	56.16	gold quality
endocervix	UBERON:0000458	55.88	gold quality
urinary bladder	UBERON:0001255	55.65	gold quality
right uterine tube	UBERON:0001302	55.51	gold quality
frontal cortex	UBERON:0001870	55.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.