SEC61G-DT

Summary

SEC61G-DT (SEC61G divergent transcript, HGNC:40835) is a long non-coding RNA gene on chromosome 7p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40835
Approved symbol	SEC61G-DT
Name	SEC61G divergent transcript
Location	7p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234707
Ensembl biotype	lncRNA
Entrez	100996654
RNAcentral	URS0000759D97 — lncRNA, 634 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000439413, ENST00000655633, ENST00000688582, ENST00000691743, ENST00000701428, ENST00000702812, ENST00000795475, ENST00000795476, ENST00000795477, ENST00000795478, ENST00000795479, ENST00000795480, ENST00000795481, ENST00000795482, ENST00000795483, ENST00000795484, ENST00000795485, ENST00000795486, ENST00000795487, ENST00000795488, ENST00000795489, ENST00000795490, ENST00000795491

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439413 — 3 exons

Exon	Start	End
ENSE00001611806	54783108	54783225
ENSE00004180228	54804666	54804971
ENSE00004180243	54759283	54759524

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 88.41.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.1940 / max 29.4849, expressed in 1094 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
78688	2.1940	1094

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	88.41	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.29	gold quality
ileal mucosa	UBERON:0000331	72.06	silver quality
pancreatic ductal cell	CL:0002079	69.51	silver quality
ventricular zone	UBERON:0003053	67.52	gold quality
left testis	UBERON:0004533	66.72	gold quality
right testis	UBERON:0004534	65.73	gold quality
testis	UBERON:0000473	65.09	gold quality
deltoid	UBERON:0001476	60.20	silver quality
islet of Langerhans	UBERON:0000006	60.03	gold quality
cortical plate	UBERON:0005343	58.57	silver quality
right uterine tube	UBERON:0001302	57.77	gold quality
pancreas	UBERON:0001264	56.97	gold quality
prefrontal cortex	UBERON:0000451	56.55	gold quality
calcaneal tendon	UBERON:0003701	56.47	gold quality
body of pancreas	UBERON:0001150	55.86	gold quality
epithelial cell of pancreas	CL:0000083	55.80	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.49	gold quality
monocyte	CL:0000576	52.70	gold quality
quadriceps femoris	UBERON:0001377	52.61	gold quality
spinal cord	UBERON:0002240	52.29	gold quality
muscle of leg	UBERON:0001383	51.78	gold quality
nucleus accumbens	UBERON:0001882	50.71	gold quality
putamen	UBERON:0001874	50.34	gold quality
myocardium	UBERON:0002349	50.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.