SEMA3F-AS1

Summary

SEMA3F-AS1 (SEMA3F antisense RNA 1, HGNC:40518) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40518
Approved symbol	SEMA3F-AS1
Name	SEMA3F antisense RNA 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	RBM5-AS1
Ensembl gene	ENSG00000235016
Ensembl biotype	lncRNA
Entrez	100129060
RNAcentral	URS00002722A5 — lncRNA, 2755 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000425674, ENST00000437204, ENST00000844078

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425674 — 2 exons

Exon	Start	End
ENSE00001735832	50118165	50118442
ENSE00001779009	50155734	50156020

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 81.62.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1440 / max 7.0543, expressed in 68 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
42291	0.1440	68

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	81.62	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.25	gold quality
blood	UBERON:0000178	76.43	gold quality
bone marrow cell	CL:0002092	76.10	gold quality
monocyte	CL:0000576	75.73	gold quality
granulocyte	CL:0000094	75.70	gold quality
leukocyte	CL:0000738	75.07	gold quality
lower esophagus mucosa	UBERON:0035834	74.12	gold quality
mucosa of transverse colon	UBERON:0004991	73.09	gold quality
spleen	UBERON:0002106	73.07	gold quality
left uterine tube	UBERON:0001303	72.56	gold quality
subcutaneous adipose tissue	UBERON:0002190	72.38	gold quality
upper lobe of left lung	UBERON:0008952	72.34	gold quality
mucosa of stomach	UBERON:0001199	72.23	gold quality
apex of heart	UBERON:0002098	72.17	gold quality
right lobe of liver	UBERON:0001114	71.82	gold quality
right adrenal gland cortex	UBERON:0035827	71.69	gold quality
adipose tissue	UBERON:0001013	71.45	gold quality
skin of abdomen	UBERON:0001416	71.25	gold quality
zone of skin	UBERON:0000014	71.02	gold quality
skin of leg	UBERON:0001511	70.94	gold quality
small intestine Peyer’s patch	UBERON:0003454	70.63	gold quality
omental fat pad	UBERON:0010414	70.60	gold quality
thoracic mammary gland	UBERON:0005200	70.52	gold quality
body of stomach	UBERON:0001161	70.31	gold quality
left adrenal gland	UBERON:0001234	70.26	gold quality
left adrenal gland cortex	UBERON:0035825	70.23	gold quality
left lobe of thyroid gland	UBERON:0001120	70.22	gold quality
cortex of kidney	UBERON:0001225	70.15	gold quality
right lobe of thyroid gland	UBERON:0001119	70.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.