SEMA5A-AS1

Summary

SEMA5A-AS1 (SEMA5A antisense RNA 1, HGNC:52973) is a long non-coding RNA gene on chromosome 5p15.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52973
Approved symbol	SEMA5A-AS1
Name	SEMA5A antisense RNA 1
Location	5p15.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251370
Ensembl biotype	lncRNA
Entrez	101929338
RNAcentral	URS0000594CAE — lncRNA, 1679 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000510879

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510879 — 3 exons

Exon	Start	End
ENSE00002022960	9511333	9511410
ENSE00002042911	9511980	9512065
ENSE00002077635	9516572	9518086

Expression profiles

Bgee: expression breadth broad, 77 present calls, max score 76.76.

Top tissues by expression

77 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
myometrium	UBERON:0001296	76.76	gold quality
sural nerve	UBERON:0015488	69.20	gold quality
tonsil	UBERON:0002372	67.54	gold quality
skeletal muscle tissue	UBERON:0001134	65.75	silver quality
corpus callosum	UBERON:0002336	64.61	gold quality
kidney	UBERON:0002113	59.94	gold quality
prostate gland	UBERON:0002367	59.85	silver quality
liver	UBERON:0002107	55.72	silver quality
adrenal gland	UBERON:0002369	55.55	gold quality
stomach	UBERON:0000945	54.09	gold quality
adrenal tissue	UBERON:0018303	53.81	gold quality
right lobe of liver	UBERON:0001114	53.60	gold quality
adult mammalian kidney	UBERON:0000082	52.78	gold quality
calcaneal tendon	UBERON:0003701	52.37	gold quality
thoracic mammary gland	UBERON:0005200	52.26	silver quality
stromal cell of endometrium	CL:0002255	52.12	silver quality
lung	UBERON:0002048	51.29	gold quality
esophagus	UBERON:0001043	50.74	silver quality
left uterine tube	UBERON:0001303	50.58	gold quality
urinary bladder	UBERON:0001255	50.48	silver quality
endometrium	UBERON:0001295	49.49	silver quality
body of uterus	UBERON:0009853	49.28	gold quality
intestine	UBERON:0000160	49.00	gold quality
uterine cervix	UBERON:0000002	48.61	silver quality
heart	UBERON:0000948	48.01	gold quality
islet of Langerhans	UBERON:0000006	47.97	silver quality
blood	UBERON:0000178	47.95	silver quality
small intestine	UBERON:0002108	46.62	silver quality
brain	UBERON:0000955	46.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	46.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.