SEMA5A-AS2

Summary

SEMA5A-AS2 (SEMA5A antisense RNA 2, HGNC:40519) is a long non-coding RNA gene on chromosome 5p15.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40519
Approved symbol	SEMA5A-AS2
Name	SEMA5A antisense RNA 2
Location	5p15.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248537
Ensembl biotype	lncRNA
Entrez	142761589

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000511310

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511310 — 4 exons

Exon	Start	End
ENSE00002021667	9422348	9422481
ENSE00002022401	9363275	9363423
ENSE00002079953	9390937	9390996
ENSE00002081573	9367348	9367395

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 92.55.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.55	gold quality
corpus callosum	UBERON:0002336	70.02	gold quality
sural nerve	UBERON:0015488	68.02	gold quality
skeletal muscle tissue	UBERON:0001134	63.37	gold quality
right coronary artery	UBERON:0001625	63.15	gold quality
muscle tissue	UBERON:0002385	62.70	gold quality
smooth muscle tissue	UBERON:0001135	62.40	gold quality
prefrontal cortex	UBERON:0000451	61.62	gold quality
left coronary artery	UBERON:0001626	61.44	gold quality
descending thoracic aorta	UBERON:0002345	60.49	gold quality
ascending aorta	UBERON:0001496	59.62	gold quality
thoracic aorta	UBERON:0001515	59.58	gold quality
placenta	UBERON:0001987	58.49	gold quality
gall bladder	UBERON:0002110	58.25	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.13	gold quality
vermiform appendix	UBERON:0001154	57.26	gold quality
calcaneal tendon	UBERON:0003701	56.39	gold quality
heart	UBERON:0000948	55.82	gold quality
cortex of kidney	UBERON:0001225	55.72	gold quality
monocyte	CL:0000576	55.02	gold quality
kidney	UBERON:0002113	54.83	gold quality
endometrium	UBERON:0001295	54.74	gold quality
blood	UBERON:0000178	54.24	silver quality
tibial artery	UBERON:0007610	54.08	gold quality
popliteal artery	UBERON:0002250	54.02	gold quality
muscle of leg	UBERON:0001383	53.80	gold quality
rectum	UBERON:0001052	53.15	gold quality
liver	UBERON:0002107	53.10	gold quality
right frontal lobe	UBERON:0002810	51.90	gold quality
fallopian tube	UBERON:0003889	51.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.