SEMA5A-AS3

Summary

SEMA5A-AS3 (SEMA5A antisense RNA 3, HGNC:59000) is a long non-coding RNA gene on chromosome 5p15.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59000
Approved symbol	SEMA5A-AS3
Name	SEMA5A antisense RNA 3
Location	5p15.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250619
Ensembl biotype	lncRNA
Entrez	144667573

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000506519

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506519 — 6 exons

Exon	Start	End
ENSE00002029525	9001774	9001894
ENSE00002029741	9042061	9042165
ENSE00002043551	9041497	9041604
ENSE00002048639	9040145	9040367
ENSE00002064338	9043166	9043277
ENSE00002068997	9045805	9045940

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 80.50.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	80.50	gold quality
colonic epithelium	UBERON:0000397	77.43	gold quality
skeletal muscle tissue	UBERON:0001134	68.29	gold quality
liver	UBERON:0002107	66.10	gold quality
small intestine	UBERON:0002108	59.15	gold quality
stromal cell of endometrium	CL:0002255	58.91	gold quality
stomach	UBERON:0000945	57.00	gold quality
urinary bladder	UBERON:0001255	55.43	gold quality
uterine cervix	UBERON:0000002	54.98	gold quality
gall bladder	UBERON:0002110	54.82	gold quality
prefrontal cortex	UBERON:0000451	54.19	gold quality
vermiform appendix	UBERON:0001154	53.26	gold quality
kidney	UBERON:0002113	53.09	gold quality
right lobe of liver	UBERON:0001114	52.37	silver quality
endometrium	UBERON:0001295	51.74	silver quality
blood	UBERON:0000178	51.19	gold quality
lymph node	UBERON:0000029	50.94	gold quality
placenta	UBERON:0001987	49.17	gold quality
ovary	UBERON:0000992	48.86	gold quality
islet of Langerhans	UBERON:0000006	47.77	gold quality
prostate gland	UBERON:0002367	47.57	gold quality
adrenal gland	UBERON:0002369	46.87	gold quality
cerebral cortex	UBERON:0000956	46.26	gold quality
intestine	UBERON:0000160	46.24	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	46.19	gold quality
adult mammalian kidney	UBERON:0000082	45.26	gold quality
tibial artery	UBERON:0007610	45.26	gold quality
gastrocnemius	UBERON:0001388	45.23	silver quality
colon	UBERON:0001155	45.19	gold quality
lung	UBERON:0002048	45.02	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.