SEPSECS-DT

Summary

SEPSECS-DT (SEPSECS divergent transcript, HGNC:27737) is a long non-coding RNA gene on chromosome 4p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27737
Approved symbol	SEPSECS-DT
Name	SEPSECS divergent transcript
Location	4p15.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281501
Ensembl biotype	lncRNA
Entrez	285540
RNAcentral	URS00007599BF — lncRNA, 1133 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000507794, ENST00000510415

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507794 — 2 exons

Exon	Start	End
ENSE00002025996	25197468	25201440
ENSE00002071121	25160672	25160753

Expression profiles

Bgee: expression breadth ubiquitous, 200 present calls, max score 96.56.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.4967 / max 108.5483, expressed in 1316 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
47123	3.9803	1412
47122	3.4967	1316
47121	0.8400	439

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	96.56	gold quality
left testis	UBERON:0004533	85.53	gold quality
right testis	UBERON:0004534	84.69	gold quality
testis	UBERON:0000473	82.72	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.95	gold quality
apex of heart	UBERON:0002098	79.55	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.00	gold quality
monocyte	CL:0000576	78.01	gold quality
leukocyte	CL:0000738	77.74	gold quality
mucosa of transverse colon	UBERON:0004991	76.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	75.78	gold quality
bone marrow cell	CL:0002092	75.30	gold quality
granulocyte	CL:0000094	74.88	gold quality
gastrocnemius	UBERON:0001388	74.74	gold quality
muscle of leg	UBERON:0001383	74.68	gold quality
colonic epithelium	UBERON:0000397	74.65	gold quality
right lobe of liver	UBERON:0001114	74.25	gold quality
blood	UBERON:0000178	73.70	gold quality
thymus	UBERON:0002370	73.51	gold quality
right adrenal gland	UBERON:0001233	73.41	gold quality
heart left ventricle	UBERON:0002084	72.89	gold quality
right adrenal gland cortex	UBERON:0035827	72.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.61	gold quality
adult mammalian kidney	UBERON:0000082	72.58	gold quality
rectum	UBERON:0001052	72.56	gold quality
lower esophagus mucosa	UBERON:0035834	72.23	gold quality
cardiac ventricle	UBERON:0002082	72.07	gold quality
left adrenal gland	UBERON:0001234	71.78	gold quality
left adrenal gland cortex	UBERON:0035825	71.72	gold quality
bone marrow	UBERON:0002371	71.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.