SEPTIN4-AS1

Summary

SEPTIN4-AS1 (SEPTIN4 antisense RNA 1, HGNC:51345) is a long non-coding RNA gene on chromosome 17q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51345
Approved symbol	SEPTIN4-AS1
Name	SEPTIN4 antisense RNA 1
Location	17q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264672
Ensembl biotype	lncRNA
Entrez	101927688
RNAcentral	URS000015693D — lncRNA, 653 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 32 lncRNA

ENST00000578022, ENST00000580589, ENST00000580769, ENST00000687131, ENST00000717184, ENST00000739998, ENST00000739999, ENST00000740000, ENST00000740001, ENST00000740002, ENST00000740003, ENST00000740004, ENST00000740005, ENST00000740006, ENST00000740007, ENST00000740008, ENST00000740009, ENST00000740010, ENST00000740032, ENST00000740039, ENST00000740040, ENST00000740041, ENST00000740042, ENST00000740043, ENST00000740044, ENST00000740045, ENST00000740046, ENST00000740047, ENST00000740048, ENST00000740049, ENST00000740050, ENST00000740051

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578022 — 4 exons

Exon	Start	End
ENSE00002699900	58556809	58557799
ENSE00002721742	58525460	58525817
ENSE00002730841	58543457	58543598
ENSE00004031847	58544536	58544671

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 79.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2878 / max 28.9681, expressed in 126 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
161926	0.2540	117
161927	0.0242	5
161928	0.0097	2

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.78	gold quality
right lobe of liver	UBERON:0001114	74.70	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.69	gold quality
bone marrow cell	CL:0002092	73.44	silver quality
cerebellar hemisphere	UBERON:0002245	73.42	gold quality
cerebellar cortex	UBERON:0002129	73.23	gold quality
cerebellum	UBERON:0002037	73.08	gold quality
spleen	UBERON:0002106	72.01	gold quality
substantia nigra	UBERON:0002038	70.39	gold quality
apex of heart	UBERON:0002098	70.38	gold quality
liver	UBERON:0002107	69.90	gold quality
Ammon’s horn	UBERON:0001954	69.81	gold quality
putamen	UBERON:0001874	69.69	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.52	gold quality
spinal cord	UBERON:0002240	69.44	gold quality
metanephros cortex	UBERON:0010533	68.29	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.24	gold quality
amygdala	UBERON:0001876	68.02	gold quality
right adrenal gland cortex	UBERON:0035827	68.01	gold quality
body of pancreas	UBERON:0001150	67.94	gold quality
right adrenal gland	UBERON:0001233	67.91	gold quality
left adrenal gland cortex	UBERON:0035825	67.89	gold quality
left adrenal gland	UBERON:0001234	67.79	gold quality
upper lobe of left lung	UBERON:0008952	67.67	gold quality
left coronary artery	UBERON:0001626	67.58	gold quality
mucosa of transverse colon	UBERON:0004991	67.57	gold quality
right frontal lobe	UBERON:0002810	67.27	gold quality
placenta	UBERON:0001987	67.26	gold quality
brain	UBERON:0000955	67.07	gold quality
ascending aorta	UBERON:0001496	66.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.