SEPTIN7-DT

Summary

SEPTIN7-DT (SEPTIN7 divergent transcript, HGNC:51153) is a long non-coding RNA gene on chromosome 7p14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51153
Approved symbol	SEPTIN7-DT
Name	SEPTIN7 divergent transcript
Location	7p14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228878
Ensembl biotype	lncRNA
Entrez	101928545
RNAcentral	URS000075D346 — lncRNA, 806 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 36 — 36 lncRNA

ENST00000412856, ENST00000424194, ENST00000437235, ENST00000658573, ENST00000665516, ENST00000670426, ENST00000692566, ENST00000736359, ENST00000736360, ENST00000736361, ENST00000736362, ENST00000736363, ENST00000736364, ENST00000736365, ENST00000736366, ENST00000736367, ENST00000736368, ENST00000736369, ENST00000736370, ENST00000736371, ENST00000736372, ENST00000736373, ENST00000736374, ENST00000736375, ENST00000736376, ENST00000736377, ENST00000736378, ENST00000736379, ENST00000736380, ENST00000736381, ENST00000736382, ENST00000736383, ENST00000736384, ENST00000736385, ENST00000736386, ENST00000736387

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412856 — 6 exons

Exon	Start	End
ENSE00001715884	35781209	35781345
ENSE00001728101	35758179	35758273
ENSE00001740133	35793906	35794022
ENSE00001776495	35755733	35755817
ENSE00004069623	35751908	35755195
ENSE00004069651	35800486	35800650

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 81.00.

FANTOM5 (CAGE): breadth broad, TPM avg 1.4048 / max 25.0367, expressed in 678 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
83561	1.4048	678

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.00	gold quality
bone marrow cell	CL:0002092	76.51	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.01	gold quality
corpus callosum	UBERON:0002336	71.21	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.91	gold quality
monocyte	CL:0000576	68.79	gold quality
islet of Langerhans	UBERON:0000006	68.74	gold quality
substantia nigra	UBERON:0002038	68.63	gold quality
amygdala	UBERON:0001876	68.24	gold quality
leukocyte	CL:0000738	68.21	gold quality
temporal lobe	UBERON:0001871	68.01	gold quality
Ammon’s horn	UBERON:0001954	66.97	gold quality
sural nerve	UBERON:0015488	66.83	silver quality
prefrontal cortex	UBERON:0000451	66.77	gold quality
putamen	UBERON:0001874	66.53	gold quality
caudate nucleus	UBERON:0001873	66.38	gold quality
hypothalamus	UBERON:0001898	66.30	gold quality
popliteal artery	UBERON:0002250	66.22	gold quality
tibial artery	UBERON:0007610	66.20	gold quality
skeletal muscle tissue	UBERON:0001134	66.15	gold quality
smooth muscle tissue	UBERON:0001135	66.12	gold quality
tibial nerve	UBERON:0001323	65.80	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.79	gold quality
nucleus accumbens	UBERON:0001882	65.72	gold quality
frontal cortex	UBERON:0001870	65.59	gold quality
brain	UBERON:0000955	65.28	gold quality
cerebral cortex	UBERON:0000956	65.26	gold quality
ventricular zone	UBERON:0003053	65.07	gold quality
adult mammalian kidney	UBERON:0000082	64.89	gold quality
ovary	UBERON:0000992	64.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.