SEPTIN9-DT

Summary

SEPTIN9-DT (SEPTIN9 divergent transcript, HGNC:52818) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52818
Approved symbol	SEPTIN9-DT
Name	SEPTIN9 divergent transcript
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263718
Ensembl biotype	lncRNA
Entrez	105371907
RNAcentral	URS0000145A68 — lncRNA, 695 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000581153, ENST00000581657, ENST00000582422, ENST00000701682, ENST00000836353, ENST00000836354, ENST00000836355, ENST00000836356, ENST00000836357

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581153 — 3 exons

Exon	Start	End
ENSE00002719752	77273784	77274041
ENSE00002725361	77281612	77281897
ENSE00002733652	77274190	77274340

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 70.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2817 / max 10.3185, expressed in 169 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
168300	0.2817	169

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	70.00	silver quality
mucosa of transverse colon	UBERON:0004991	65.17	gold quality
placenta	UBERON:0001987	59.84	gold quality
urinary bladder	UBERON:0001255	59.48	gold quality
right testis	UBERON:0004534	58.64	gold quality
left testis	UBERON:0004533	57.25	gold quality
testis	UBERON:0000473	56.78	gold quality
blood	UBERON:0000178	55.24	gold quality
lung	UBERON:0002048	54.98	gold quality
upper lobe of left lung	UBERON:0008952	54.43	gold quality
esophagus mucosa	UBERON:0002469	54.38	gold quality
liver	UBERON:0002107	54.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.73	gold quality
esophagus	UBERON:0001043	53.43	gold quality
prostate gland	UBERON:0002367	52.97	gold quality
rectum	UBERON:0001052	52.70	gold quality
transverse colon	UBERON:0001157	52.28	gold quality
vermiform appendix	UBERON:0001154	52.19	gold quality
body of stomach	UBERON:0001161	52.14	gold quality
stomach	UBERON:0000945	52.07	gold quality
lymph node	UBERON:0000029	51.98	gold quality
colon	UBERON:0001155	51.84	gold quality
gall bladder	UBERON:0002110	51.55	gold quality
nucleus accumbens	UBERON:0001882	51.21	gold quality
fundus of stomach	UBERON:0001160	51.14	gold quality
monocyte	CL:0000576	51.05	silver quality
right lobe of liver	UBERON:0001114	51.00	gold quality
intestine	UBERON:0000160	50.21	gold quality
multicellular organism	UBERON:0000468	50.06	gold quality
skin of abdomen	UBERON:0001416	49.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.