SERINC5-AS1

Summary

SERINC5-AS1 (SERINC5 antisense RNA 1, HGNC:59087) is a long non-coding RNA gene on chromosome 5q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59087
Approved symbol	SERINC5-AS1
Name	SERINC5 antisense RNA 1
Location	5q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251675
Ensembl biotype	lncRNA
Entrez	144717125

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000511484

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511484 — 3 exons

Exon	Start	End
ENSE00002024227	80128361	80128415
ENSE00002043933	80128923	80129197
ENSE00002053123	80143550	80143883

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 83.66.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.17	gold quality
monocyte	CL:0000576	74.88	gold quality
leukocyte	CL:0000738	73.66	gold quality
ganglionic eminence	UBERON:0004023	71.61	gold quality
endometrium	UBERON:0001295	70.65	gold quality
bone marrow cell	CL:0002092	69.48	silver quality
liver	UBERON:0002107	66.32	gold quality
right lobe of liver	UBERON:0001114	66.17	gold quality
colonic epithelium	UBERON:0000397	65.40	silver quality
right adrenal gland cortex	UBERON:0035827	65.03	gold quality
lower esophagus mucosa	UBERON:0035834	63.52	gold quality
mucosa of transverse colon	UBERON:0004991	62.75	gold quality
right adrenal gland	UBERON:0001233	62.58	gold quality
tonsil	UBERON:0002372	62.57	gold quality
left adrenal gland	UBERON:0001234	62.28	gold quality
left adrenal gland cortex	UBERON:0035825	62.09	gold quality
adrenal gland	UBERON:0002369	61.68	gold quality
blood	UBERON:0000178	61.18	gold quality
rectum	UBERON:0001052	60.58	gold quality
bone marrow	UBERON:0002371	60.20	gold quality
esophagus mucosa	UBERON:0002469	59.31	gold quality
skin of abdomen	UBERON:0001416	59.04	gold quality
left ovary	UBERON:0002119	58.53	gold quality
zone of skin	UBERON:0000014	58.49	gold quality
lymph node	UBERON:0000029	58.35	gold quality
prostate gland	UBERON:0002367	58.28	gold quality
skin of leg	UBERON:0001511	58.06	gold quality
ovary	UBERON:0000992	57.67	gold quality
vagina	UBERON:0000996	57.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.