SETBP1-DT

Summary

SETBP1-DT (SETBP1 divergent transcript, HGNC:54819) is a long non-coding RNA gene on chromosome 18q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54819
Approved symbol	SETBP1-DT
Name	SETBP1 divergent transcript
Location	18q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267414
Ensembl biotype	lncRNA
Entrez	101927943
RNAcentral	URS0002A146B5 — lncRNA, 2216 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000592638

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000592638 — 2 exons

Exon	Start	End
ENSE00002885278	44679616	44679717
ENSE00002901355	44676927	44678889

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 76.14.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2150 / max 41.9765, expressed in 79 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
171767	0.2150	79

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	76.14	gold quality
right coronary artery	UBERON:0001625	74.24	gold quality
ganglionic eminence	UBERON:0004023	73.97	gold quality
tibial artery	UBERON:0007610	72.06	gold quality
popliteal artery	UBERON:0002250	72.04	gold quality
left coronary artery	UBERON:0001626	71.99	gold quality
aorta	UBERON:0000947	70.62	gold quality
smooth muscle tissue	UBERON:0001135	70.57	gold quality
metanephros cortex	UBERON:0010533	70.57	gold quality
coronary artery	UBERON:0001621	70.45	gold quality
descending thoracic aorta	UBERON:0002345	69.51	gold quality
thoracic aorta	UBERON:0001515	69.14	gold quality
calcaneal tendon	UBERON:0003701	69.13	gold quality
ascending aorta	UBERON:0001496	68.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.42	gold quality
left uterine tube	UBERON:0001303	65.49	gold quality
tibia	UBERON:0000979	65.43	silver quality
visceral pleura	UBERON:0002401	65.33	silver quality
upper lobe of left lung	UBERON:0008952	65.25	gold quality
right lung	UBERON:0002167	65.23	gold quality
endocervix	UBERON:0000458	65.18	gold quality
upper lobe of lung	UBERON:0008948	64.58	gold quality
islet of Langerhans	UBERON:0000006	64.49	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.03	gold quality
cortical plate	UBERON:0005343	63.93	gold quality
body of uterus	UBERON:0009853	63.89	gold quality
prefrontal cortex	UBERON:0000451	63.54	gold quality
muscle of leg	UBERON:0001383	63.42	gold quality
muscle layer of sigmoid colon	UBERON:0035805	63.35	gold quality
adult mammalian kidney	UBERON:0000082	63.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.