SEZ6L-AS1

Summary

SEZ6L-AS1 (SEZ6L antisense RNA 1, HGNC:40521) is a long non-coding RNA gene on chromosome 22q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40521
Approved symbol	SEZ6L-AS1
Name	SEZ6L antisense RNA 1
Location	22q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224192
Ensembl biotype	lncRNA
Entrez	105372974
RNAcentral	URS00001D1E81 — lncRNA, 535 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000414989

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414989 — 5 exons

Exon	Start	End
ENSE00001633551	26244618	26244689
ENSE00001667638	26244337	26244495
ENSE00001673962	26241331	26241411
ENSE00001740251	26253974	26254092
ENSE00001772052	26242752	26242855

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 57.33.

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	57.33	gold quality
left testis	UBERON:0004533	55.98	gold quality
testis	UBERON:0000473	55.64	gold quality
right testis	UBERON:0004534	55.41	gold quality
prefrontal cortex	UBERON:0000451	53.95	gold quality
corpus callosum	UBERON:0002336	53.88	gold quality
islet of Langerhans	UBERON:0000006	52.92	gold quality
pancreas	UBERON:0001264	52.13	gold quality
primary visual cortex	UBERON:0002436	50.21	gold quality
blood	UBERON:0000178	49.62	silver quality
calcaneal tendon	UBERON:0003701	48.68	silver quality
cerebellum	UBERON:0002037	47.51	gold quality
cerebellar cortex	UBERON:0002129	47.45	gold quality
cerebellar hemisphere	UBERON:0002245	46.76	gold quality
nucleus accumbens	UBERON:0001882	45.73	gold quality
right hemisphere of cerebellum	UBERON:0014890	45.72	gold quality
liver	UBERON:0002107	45.56	silver quality
Brodmann (1909) area 9	UBERON:0013540	45.24	gold quality
brain	UBERON:0000955	45.10	gold quality
adrenal gland	UBERON:0002369	45.10	gold quality
amygdala	UBERON:0001876	44.81	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	44.73	gold quality
anterior cingulate cortex	UBERON:0009835	44.16	gold quality
gastrocnemius	UBERON:0001388	43.82	silver quality
superior frontal gyrus	UBERON:0002661	43.74	silver quality
Ammon’s horn	UBERON:0001954	42.85	gold quality
substantia nigra	UBERON:0002038	42.61	gold quality
body of pancreas	UBERON:0001150	42.58	silver quality
putamen	UBERON:0001874	42.40	gold quality
hypothalamus	UBERON:0001898	42.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.