SGSM2-AS1

Summary

SGSM2-AS1 (SGSM2 antisense RNA 1, HGNC:56091) is a long non-coding RNA gene on chromosome 17p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56091
Approved symbol	SGSM2-AS1
Name	SGSM2 antisense RNA 1
Location	17p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP1-59D14.5
Ensembl gene	ENSG00000263345
Ensembl biotype	lncRNA
Entrez	123706538
RNAcentral	URS00001DDA2C — lncRNA, 846 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000573007, ENST00000574290

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000573007 — 2 exons

Exon	Start	End
ENSE00002655586	2376799	2376852
ENSE00002658067	2377359	2377746

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 91.19.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pituitary gland	UBERON:0000007	91.19	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.66	gold quality
adenohypophysis	UBERON:0002196	88.89	gold quality
right frontal lobe	UBERON:0002810	85.68	gold quality
lower esophagus mucosa	UBERON:0035834	85.46	gold quality
prostate gland	UBERON:0002367	85.38	gold quality
muscle layer of sigmoid colon	UBERON:0035805	84.90	gold quality
metanephros cortex	UBERON:0010533	83.68	gold quality
lower esophagus	UBERON:0013473	83.47	gold quality
lower esophagus muscularis layer	UBERON:0035833	83.47	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	83.41	gold quality
right lobe of thyroid gland	UBERON:0001119	83.30	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.23	gold quality
fundus of stomach	UBERON:0001160	83.20	gold quality
left lobe of thyroid gland	UBERON:0001120	83.02	gold quality
thyroid gland	UBERON:0002046	82.76	gold quality
endocervix	UBERON:0000458	82.57	gold quality
minor salivary gland	UBERON:0001830	82.29	gold quality
ectocervix	UBERON:0012249	82.10	gold quality
vagina	UBERON:0000996	81.97	gold quality
saliva-secreting gland	UBERON:0001044	81.80	gold quality
cerebellar hemisphere	UBERON:0002245	81.58	gold quality
body of uterus	UBERON:0009853	81.58	gold quality
right uterine tube	UBERON:0001302	81.42	gold quality
nucleus accumbens	UBERON:0001882	81.36	gold quality
esophagus	UBERON:0001043	81.32	gold quality
cerebellar cortex	UBERON:0002129	81.24	gold quality
left ovary	UBERON:0002119	81.15	gold quality
cerebellum	UBERON:0002037	81.10	gold quality
right adrenal gland cortex	UBERON:0035827	81.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.