SH3TC2-DT

Summary

SH3TC2-DT (SH3TC2 divergent transcript, HGNC:52905) is a long non-coding RNA gene on chromosome 5q32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52905
Approved symbol	SH3TC2-DT
Name	SH3TC2 divergent transcript
Location	5q32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250072
Ensembl biotype	lncRNA
Entrez	255187
RNAcentral	URS000075B781 — lncRNA, 813 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 41 — 41 lncRNA

ENST00000507318, ENST00000507373, ENST00000509139, ENST00000512007, ENST00000515304, ENST00000515519, ENST00000668914, ENST00000685416, ENST00000701848, ENST00000787317, ENST00000787318, ENST00000787319, ENST00000787320, ENST00000787321, ENST00000787322, ENST00000787323, ENST00000787324, ENST00000787325, ENST00000787326, ENST00000787327, ENST00000787328, ENST00000787329, ENST00000787330, ENST00000787331, ENST00000787332, ENST00000787333, ENST00000787334, ENST00000787335, ENST00000787336, ENST00000787337, ENST00000787338, ENST00000787339, ENST00000787340, ENST00000787341, ENST00000787342, ENST00000787343, ENST00000787344, ENST00000787345, ENST00000787346, ENST00000787347, ENST00000787348

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507318 — 2 exons

Exon	Start	End
ENSE00002020377	149064067	149066985
ENSE00002033624	149063503	149063674

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 98.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2594 / max 54.2742, expressed in 111 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
59339	0.1074	42
59342	0.0884	40
59338	0.0292	17
59341	0.0178	8
59340	0.0166	7

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	98.44	gold quality
corpus callosum	UBERON:0002336	87.33	gold quality
sural nerve	UBERON:0015488	85.75	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	75.86	gold quality
substantia nigra	UBERON:0002038	68.12	gold quality
tibial nerve	UBERON:0001323	67.27	gold quality
placenta	UBERON:0001987	67.14	gold quality
ventricular zone	UBERON:0003053	63.84	gold quality
skeletal muscle tissue	UBERON:0001134	63.12	gold quality
prefrontal cortex	UBERON:0000451	62.87	gold quality
Ammon’s horn	UBERON:0001954	61.39	gold quality
primary visual cortex	UBERON:0002436	61.35	gold quality
apex of heart	UBERON:0002098	61.26	gold quality
monocyte	CL:0000576	60.71	gold quality
frontal cortex	UBERON:0001870	58.97	gold quality
right testis	UBERON:0004534	58.91	gold quality
testis	UBERON:0000473	58.90	gold quality
left testis	UBERON:0004533	58.82	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.82	gold quality
right atrium auricular region	UBERON:0006631	58.60	gold quality
hypothalamus	UBERON:0001898	58.11	gold quality
liver	UBERON:0002107	57.55	gold quality
heart	UBERON:0000948	57.03	gold quality
heart left ventricle	UBERON:0002084	57.00	gold quality
putamen	UBERON:0001874	56.80	gold quality
cerebral cortex	UBERON:0000956	56.75	gold quality
calcaneal tendon	UBERON:0003701	56.48	gold quality
duodenum	UBERON:0002114	56.41	gold quality
brain	UBERON:0000955	55.62	gold quality
amygdala	UBERON:0001876	55.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.