SHANK2-AS3

Summary

SHANK2-AS3 (SHANK2 antisense RNA 3, HGNC:25098) is a long non-coding RNA gene on chromosome 11q13.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:25098
Approved symbol	SHANK2-AS3
Name	SHANK2 antisense RNA 3
Location	11q13.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000171671
Ensembl biotype	lncRNA
Entrez	220070
RNAcentral	URS000075D7DD — lncRNA, 1702 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000307548

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000307548 — 3 exons

Exon	Start	End
ENSE00001646749	70863788	70865115
ENSE00001682695	70863285	70863561
ENSE00001693135	70862790	70862867

Expression profiles

Bgee: expression breadth broad, 38 present calls, max score 76.45.

Top tissues by expression

157 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
upper arm skin	UBERON:0004263	76.45	gold quality
nasal cavity epithelium	UBERON:0005384	74.09	gold quality
pancreatic ductal cell	CL:0002079	72.76	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	72.17	gold quality
myocardium	UBERON:0002349	71.80	gold quality
epithelial cell of pancreas	CL:0000083	70.91	gold quality
bone marrow	UBERON:0002371	69.21	gold quality
cardiac muscle of right atrium	UBERON:0003379	68.90	gold quality
left ventricle myocardium	UBERON:0006566	68.43	gold quality
sperm	CL:0000019	66.64	gold quality
parotid gland	UBERON:0001831	65.87	gold quality
kidney epithelium	UBERON:0004819	65.46	gold quality
quadriceps femoris	UBERON:0001377	63.24	gold quality
deltoid	UBERON:0001476	62.93	gold quality
pericardium	UBERON:0002407	62.80	silver quality
vastus lateralis	UBERON:0001379	62.54	gold quality
Brodmann (1909) area 46	UBERON:0006483	62.35	gold quality
ileal mucosa	UBERON:0000331	62.20	silver quality
layer of synovial tissue	UBERON:0007616	61.83	gold quality
secondary oocyte	CL:0000655	61.59	gold quality
saphenous vein	UBERON:0007318	60.92	gold quality
mucosa of sigmoid colon	UBERON:0004993	60.49	gold quality
tonsil	UBERON:0002372	60.44	silver quality
mammary duct	UBERON:0001765	60.15	gold quality
epithelium of mammary gland	UBERON:0003244	60.13	gold quality
inferior vagus X ganglion	UBERON:0005363	59.61	gold quality
colonic mucosa	UBERON:0000317	59.60	gold quality
subthalamic nucleus	UBERON:0001906	59.60	gold quality
blood	UBERON:0000178	59.56	gold quality
pharyngeal mucosa	UBERON:0000355	59.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.