SHROOM3-AS1

Summary

SHROOM3-AS1 (SHROOM3 antisense RNA 1, HGNC:41265) is a long non-coding RNA gene on chromosome 4q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41265
Approved symbol	SHROOM3-AS1
Name	SHROOM3 antisense RNA 1
Location	4q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233860
Ensembl biotype	lncRNA
Entrez	105377289
RNAcentral	URS00026A2649 — lncRNA, 1533 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000449007, ENST00000452412, ENST00000660459, ENST00000666047, ENST00000666924, ENST00000668373, ENST00000669577, ENST00000747876, ENST00000747877, ENST00000747878, ENST00000747879, ENST00000747880, ENST00000747881, ENST00000747882, ENST00000747883, ENST00000747884, ENST00000747885, ENST00000747886, ENST00000747887

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449007 — 2 exons

Exon	Start	End
ENSE00004090423	76758092	76758592
ENSE00004090424	76801894	76801977

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 84.69.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.69	gold quality
sural nerve	UBERON:0015488	79.90	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.28	gold quality
colonic epithelium	UBERON:0000397	77.72	gold quality
mucosa of stomach	UBERON:0001199	71.05	gold quality
bone marrow cell	CL:0002092	69.78	silver quality
tonsil	UBERON:0002372	67.77	gold quality
cortical plate	UBERON:0005343	67.51	gold quality
smooth muscle tissue	UBERON:0001135	67.24	gold quality
ventricular zone	UBERON:0003053	67.16	gold quality
ganglionic eminence	UBERON:0004023	66.67	gold quality
gall bladder	UBERON:0002110	66.20	gold quality
lower esophagus mucosa	UBERON:0035834	64.83	gold quality
liver	UBERON:0002107	64.72	gold quality
prefrontal cortex	UBERON:0000451	64.13	gold quality
rectum	UBERON:0001052	63.60	gold quality
endometrium	UBERON:0001295	63.57	gold quality
ascending aorta	UBERON:0001496	63.25	gold quality
thoracic aorta	UBERON:0001515	62.89	gold quality
stomach	UBERON:0000945	62.14	gold quality
placenta	UBERON:0001987	62.02	gold quality
ovary	UBERON:0000992	62.01	gold quality
left ovary	UBERON:0002119	61.82	gold quality
superior frontal gyrus	UBERON:0002661	61.66	gold quality
adrenal tissue	UBERON:0018303	61.08	gold quality
frontal cortex	UBERON:0001870	60.94	gold quality
lung	UBERON:0002048	60.92	gold quality
descending thoracic aorta	UBERON:0002345	60.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.79	gold quality
mucosa of transverse colon	UBERON:0004991	60.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.