SIAH2-AS1

Summary

SIAH2-AS1 (SIAH2 and CLRN1 antisense RNA 1, HGNC:40526) is a long non-coding RNA gene on chromosome 3q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40526
Approved symbol	SIAH2-AS1
Name	SIAH2 and CLRN1 antisense RNA 1
Location	3q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244265
Ensembl biotype	lncRNA
Entrez	105374155
RNAcentral	URS00026A1B62 — lncRNA, 441 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000461943, ENST00000465576, ENST00000476886, ENST00000663257, ENST00000693001, ENST00000715814, ENST00000715815, ENST00000715816, ENST00000715817, ENST00000715818, ENST00000715819, ENST00000715820, ENST00000715821, ENST00000715822, ENST00000716210, ENST00000716211

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000461943 — 2 exons

Exon	Start	End
ENSE00001852326	150761937	150762175
ENSE00001881637	150762337	150762538

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 99.85.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7831 / max 15.0808, expressed in 345 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
39213	0.7831	345
39215	0.0234	8

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
secondary oocyte	CL:0000655	99.85	gold quality
oocyte	CL:0000023	97.70	gold quality
buccal mucosa cell	CL:0002336	93.05	silver quality
pancreatic ductal cell	CL:0002079	91.95	silver quality
cauda epididymis	UBERON:0004360	81.03	gold quality
left ventricle myocardium	UBERON:0006566	78.23	gold quality
cardiac muscle of right atrium	UBERON:0003379	77.77	gold quality
bone marrow cell	CL:0002092	74.63	gold quality
ileal mucosa	UBERON:0000331	74.52	silver quality
kidney epithelium	UBERON:0004819	74.51	gold quality
mucosa of paranasal sinus	UBERON:0005030	73.97	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.33	gold quality
caput epididymis	UBERON:0004358	72.28	gold quality
corpus epididymis	UBERON:0004359	71.72	gold quality
germinal epithelium of ovary	UBERON:0001304	70.44	gold quality
deltoid	UBERON:0001476	70.10	gold quality
superficial temporal artery	UBERON:0001614	69.60	silver quality
myocardium	UBERON:0002349	69.19	gold quality
nasal cavity epithelium	UBERON:0005384	69.18	gold quality
right adrenal gland cortex	UBERON:0035827	69.06	gold quality
ganglionic eminence	UBERON:0004023	68.83	gold quality
adrenal tissue	UBERON:0018303	68.64	gold quality
nipple	UBERON:0002030	68.54	gold quality
left adrenal gland cortex	UBERON:0035825	68.03	gold quality
vastus lateralis	UBERON:0001379	68.01	gold quality
left adrenal gland	UBERON:0001234	67.97	gold quality
ventricular zone	UBERON:0003053	67.48	gold quality
adrenal gland	UBERON:0002369	67.30	gold quality
calcaneal tendon	UBERON:0003701	67.22	gold quality
urethra	UBERON:0000057	67.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.84

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.