SIGLEC10-AS1

Summary

SIGLEC10-AS1 (SIGLEC10 antisense RNA 1, HGNC:40719) is a long non-coding RNA gene on chromosome 19q13.41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40719
Approved symbol	SIGLEC10-AS1
Name	SIGLEC10 antisense RNA 1
Location	19q13.41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255441
Ensembl biotype	lncRNA
Entrez	100129083
RNAcentral	URS0000EEACAF — lncRNA, 1683 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000526996, ENST00000532688

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526996 — 2 exons

Exon	Start	End
ENSE00002168263	51415724	51416132
ENSE00002183171	51416429	51416646

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 89.48.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	89.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.31	silver quality
blood	UBERON:0000178	75.16	gold quality
bone marrow	UBERON:0002371	72.72	gold quality
bone marrow cell	CL:0002092	71.71	silver quality
spleen	UBERON:0002106	69.75	gold quality
left ovary	UBERON:0002119	68.07	gold quality
ovary	UBERON:0000992	67.67	gold quality
right ovary	UBERON:0002118	66.50	gold quality
ventricular zone	UBERON:0003053	66.20	gold quality
ganglionic eminence	UBERON:0004023	65.35	gold quality
leukocyte	CL:0000738	64.79	gold quality
vermiform appendix	UBERON:0001154	64.54	gold quality
monocyte	CL:0000576	63.62	gold quality
left testis	UBERON:0004533	60.09	gold quality
testis	UBERON:0000473	59.41	gold quality
lymph node	UBERON:0000029	59.03	gold quality
right testis	UBERON:0004534	58.99	gold quality
duodenum	UBERON:0002114	57.89	gold quality
endometrium	UBERON:0001295	55.40	gold quality
left adrenal gland	UBERON:0001234	55.09	gold quality
adrenal gland	UBERON:0002369	54.77	gold quality
upper lobe of left lung	UBERON:0008952	54.65	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.62	gold quality
right adrenal gland	UBERON:0001233	54.60	gold quality
liver	UBERON:0002107	54.35	gold quality
gall bladder	UBERON:0002110	54.33	gold quality
stromal cell of endometrium	CL:0002255	54.32	silver quality
prefrontal cortex	UBERON:0000451	54.21	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	7.95
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.