SIGLEC10-AS2

Summary

SIGLEC10-AS2 (SIGLEC10 antisense RNA 2, HGNC:40718) is a long non-coding RNA gene on chromosome 19q13.41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40718
Approved symbol	SIGLEC10-AS2
Name	SIGLEC10 antisense RNA 2
Location	19q13.41
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC008750.1
Ensembl gene	ENSG00000254760
Ensembl biotype	lncRNA
Entrez	127379722
RNAcentral	URS0000481857 — lncRNA, 492 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000532473

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532473 — 2 exons

Exon	Start	End
ENSE00002180799	51414712	51414965
ENSE00002181687	51414298	51414535

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 90.21.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	90.21	gold quality
blood	UBERON:0000178	80.13	gold quality
spleen	UBERON:0002106	77.47	gold quality
bone marrow	UBERON:0002371	72.79	gold quality
vermiform appendix	UBERON:0001154	72.70	gold quality
tonsil	UBERON:0002372	71.52	gold quality
ventricular zone	UBERON:0003053	70.00	gold quality
lymph node	UBERON:0000029	68.95	gold quality
bone marrow cell	CL:0002092	66.60	silver quality
ganglionic eminence	UBERON:0004023	65.90	gold quality
left adrenal gland	UBERON:0001234	64.80	gold quality
leukocyte	CL:0000738	64.79	gold quality
adrenal gland	UBERON:0002369	64.18	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.09	gold quality
monocyte	CL:0000576	63.96	gold quality
right adrenal gland	UBERON:0001233	63.13	gold quality
left adrenal gland cortex	UBERON:0035825	62.78	gold quality
right adrenal gland cortex	UBERON:0035827	61.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	60.75	gold quality
skeletal muscle tissue	UBERON:0001134	60.71	silver quality
small intestine	UBERON:0002108	60.52	gold quality
small intestine Peyer’s patch	UBERON:0003454	60.48	gold quality
mucosa of transverse colon	UBERON:0004991	60.16	gold quality
upper lobe of left lung	UBERON:0008952	60.13	gold quality
substantia nigra	UBERON:0002038	59.65	gold quality
lung	UBERON:0002048	58.49	gold quality
prefrontal cortex	UBERON:0000451	57.97	gold quality
gall bladder	UBERON:0002110	57.80	gold quality
liver	UBERON:0002107	57.40	gold quality
lower esophagus mucosa	UBERON:0035834	57.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.39

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.