SIL1-AS1

Summary

SIL1-AS1 (SIL1 antisense RNA 1, HGNC:41056) is a long non-coding RNA gene on chromosome 5q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41056
Approved symbol	SIL1-AS1
Name	SIL1 antisense RNA 1
Location	5q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249593
Ensembl biotype	lncRNA
Entrez	124901080

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000504658, ENST00000510110, ENST00000512875, ENST00000514207, ENST00000758801, ENST00000758802

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504658 — 2 exons

Exon	Start	End
ENSE00002050666	139013559	139014224
ENSE00002057841	139012650	139012786

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 82.86.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.86	gold quality
bone marrow cell	CL:0002092	79.44	gold quality
colonic epithelium	UBERON:0000397	78.11	gold quality
sural nerve	UBERON:0015488	76.42	gold quality
corpus callosum	UBERON:0002336	75.91	gold quality
skeletal muscle tissue	UBERON:0001134	71.40	gold quality
bone marrow	UBERON:0002371	70.10	gold quality
duodenum	UBERON:0002114	69.57	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.12	gold quality
calcaneal tendon	UBERON:0003701	66.31	gold quality
adrenal tissue	UBERON:0018303	66.12	gold quality
muscle tissue	UBERON:0002385	64.66	gold quality
liver	UBERON:0002107	64.63	gold quality
tonsil	UBERON:0002372	64.33	gold quality
ventricular zone	UBERON:0003053	62.60	gold quality
subcutaneous adipose tissue	UBERON:0002190	62.34	gold quality
ganglionic eminence	UBERON:0004023	62.15	gold quality
adipose tissue	UBERON:0001013	59.78	gold quality
urinary bladder	UBERON:0001255	59.62	gold quality
uterine cervix	UBERON:0000002	59.49	gold quality
thoracic mammary gland	UBERON:0005200	59.03	gold quality
gall bladder	UBERON:0002110	58.72	gold quality
kidney	UBERON:0002113	58.07	gold quality
monocyte	CL:0000576	58.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.87	gold quality
stromal cell of endometrium	CL:0002255	57.40	gold quality
apex of heart	UBERON:0002098	57.35	gold quality
right coronary artery	UBERON:0001625	57.09	gold quality
blood	UBERON:0000178	56.97	gold quality
muscle of leg	UBERON:0001383	56.51	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.