SIM1-AS1

Summary

SIM1-AS1 (SIM1 antisense RNA 1, HGNC:40530) is a long non-coding RNA gene on chromosome 6q16.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40530
Approved symbol	SIM1-AS1
Name	SIM1 antisense RNA 1
Location	6q16.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228082
Ensembl biotype	lncRNA
Entrez	102724406
RNAcentral	URS00026A26EC — lncRNA, 8582 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000411442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411442 — 2 exons

Exon	Start	End
ENSE00001597486	100437256	100437484
ENSE00001733878	100427118	100427268

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 91.97.

Top tissues by expression

54 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.97	gold quality
omental fat pad	UBERON:0010414	69.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.63	gold quality
skeletal muscle tissue	UBERON:0001134	68.45	silver quality
prefrontal cortex	UBERON:0000451	60.16	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.73	gold quality
islet of Langerhans	UBERON:0000006	57.08	gold quality
kidney	UBERON:0002113	56.72	gold quality
left testis	UBERON:0004533	56.17	gold quality
testis	UBERON:0000473	55.86	gold quality
muscle of leg	UBERON:0001383	55.59	gold quality
heart left ventricle	UBERON:0002084	55.51	gold quality
adult mammalian kidney	UBERON:0000082	53.97	gold quality
gastrocnemius	UBERON:0001388	53.83	gold quality
heart	UBERON:0000948	53.49	gold quality
blood	UBERON:0000178	53.11	silver quality
right lobe of liver	UBERON:0001114	52.12	gold quality
right testis	UBERON:0004534	51.85	gold quality
multicellular organism	UBERON:0000468	51.36	gold quality
metanephros cortex	UBERON:0010533	50.73	gold quality
body of pancreas	UBERON:0001150	49.68	gold quality
liver	UBERON:0002107	49.48	silver quality
substantia nigra	UBERON:0002038	48.77	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.19	gold quality
cerebellar hemisphere	UBERON:0002245	48.11	gold quality
stomach	UBERON:0000945	47.82	gold quality
monocyte	CL:0000576	47.59	silver quality
colon	UBERON:0001155	47.51	gold quality
subcutaneous adipose tissue	UBERON:0002190	47.41	gold quality
body of stomach	UBERON:0001161	47.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.