SIRPG-AS1

Summary

SIRPG-AS1 (SIRPG antisense RNA 1, HGNC:51229) is a long non-coding RNA gene on chromosome 20p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51229
Approved symbol	SIRPG-AS1
Name	SIRPG antisense RNA 1
Location	20p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237914
Ensembl biotype	lncRNA
Entrez	101929010
RNAcentral	URS000075E15C — lncRNA, 2796 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000437384, ENST00000456177

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437384 — 4 exons

Exon	Start	End
ENSE00001623092	1637618	1637742
ENSE00001743188	1638410	1638454
ENSE00001743974	1637206	1637350
ENSE00001795300	1633626	1633720

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 76.16.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0337 / max 10.0767, expressed in 13 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
183101	0.0337	13

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.16	gold quality
lymph node	UBERON:0000029	72.55	gold quality
colonic epithelium	UBERON:0000397	71.49	gold quality
tonsil	UBERON:0002372	69.15	gold quality
skeletal muscle tissue	UBERON:0001134	67.52	gold quality
vermiform appendix	UBERON:0001154	65.94	gold quality
blood	UBERON:0000178	65.65	gold quality
granulocyte	CL:0000094	65.20	gold quality
bone marrow	UBERON:0002371	63.79	gold quality
bone marrow cell	CL:0002092	61.38	silver quality
rectum	UBERON:0001052	60.93	gold quality
spleen	UBERON:0002106	59.75	gold quality
duodenum	UBERON:0002114	59.04	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.83	gold quality
small intestine Peyer’s patch	UBERON:0003454	57.63	gold quality
small intestine	UBERON:0002108	57.52	gold quality
prefrontal cortex	UBERON:0000451	56.26	gold quality
leukocyte	CL:0000738	55.57	gold quality
gall bladder	UBERON:0002110	54.49	gold quality
monocyte	CL:0000576	54.09	gold quality
intestine	UBERON:0000160	53.78	gold quality
right coronary artery	UBERON:0001625	53.58	gold quality
urinary bladder	UBERON:0001255	53.52	gold quality
primary visual cortex	UBERON:0002436	53.33	gold quality
superior frontal gyrus	UBERON:0002661	53.15	gold quality
gastrocnemius	UBERON:0001388	52.44	gold quality
multicellular organism	UBERON:0000468	52.05	gold quality
liver	UBERON:0002107	51.63	gold quality
right lobe of liver	UBERON:0001114	51.19	gold quality
colon	UBERON:0001155	51.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.