SLC12A5-AS1

Summary

SLC12A5-AS1 (SLC12A5 and MMP9 antisense RNA 1, HGNC:53143) is a long non-coding RNA gene on chromosome 20q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53143
Approved symbol	SLC12A5-AS1
Name	SLC12A5 and MMP9 antisense RNA 1
Location	20q13.12
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-465L10.10
Ensembl gene	ENSG00000204044
Ensembl biotype	lncRNA
Entrez	109729184
RNAcentral	URS00003FB8AF — lncRNA, 1955 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000419897, ENST00000535913

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419897 — 2 exons

Exon	Start	End
ENSE00001615672	46020619	46020905
ENSE00001767124	46021524	46021727

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 81.19.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.19	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.79	gold quality
bone marrow cell	CL:0002092	69.23	silver quality
blood	UBERON:0000178	66.75	gold quality
bone marrow	UBERON:0002371	66.37	gold quality
cortical plate	UBERON:0005343	62.55	gold quality
islet of Langerhans	UBERON:0000006	62.06	gold quality
adrenal tissue	UBERON:0018303	59.85	gold quality
pancreas	UBERON:0001264	58.03	gold quality
prefrontal cortex	UBERON:0000451	57.89	gold quality
ventricular zone	UBERON:0003053	57.31	silver quality
ganglionic eminence	UBERON:0004023	57.01	silver quality
pituitary gland	UBERON:0000007	56.72	gold quality
spleen	UBERON:0002106	56.60	gold quality
nucleus accumbens	UBERON:0001882	55.48	gold quality
adenohypophysis	UBERON:0002196	55.42	gold quality
hypothalamus	UBERON:0001898	55.39	gold quality
frontal cortex	UBERON:0001870	55.08	gold quality
putamen	UBERON:0001874	55.06	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.60	gold quality
Ammon’s horn	UBERON:0001954	54.42	gold quality
cerebral cortex	UBERON:0000956	54.29	gold quality
anterior cingulate cortex	UBERON:0009835	54.22	gold quality
brain	UBERON:0000955	54.05	gold quality
superior frontal gyrus	UBERON:0002661	54.01	gold quality
caudate nucleus	UBERON:0001873	54.00	gold quality
right adrenal gland	UBERON:0001233	53.85	gold quality
placenta	UBERON:0001987	53.60	gold quality
right lung	UBERON:0002167	53.45	gold quality
adrenal gland	UBERON:0002369	53.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.39

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.