SLC1A3-AS1

Summary

SLC1A3-AS1 (SLC1A3 antisense RNA 1, HGNC:56374) is a long non-coding RNA gene on chromosome 5p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56374
Approved symbol	SLC1A3-AS1
Name	SLC1A3 antisense RNA 1
Location	5p13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC008957.1, CTD-2353F22.1
Ensembl gene	ENSG00000250155
Ensembl biotype	lncRNA
Entrez	107986412
RNAcentral	URS0002A70391 — lncRNA, 2358 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000508745, ENST00000510740, ENST00000512329, ENST00000659180, ENST00000750858, ENST00000750859, ENST00000750860, ENST00000750861, ENST00000750862, ENST00000750863

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508745 — 3 exons

Exon	Start	End
ENSE00002035920	36705680	36705851
ENSE00003986693	36700881	36702964
ENSE00004095588	36725114	36725215

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 86.00.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	86.00	gold quality
monocyte	CL:0000576	84.70	gold quality
leukocyte	CL:0000738	84.26	gold quality
lymph node	UBERON:0000029	78.77	gold quality
granulocyte	CL:0000094	78.24	gold quality
bone marrow cell	CL:0002092	76.90	gold quality
bone marrow	UBERON:0002371	76.39	gold quality
tonsil	UBERON:0002372	73.13	gold quality
cortical plate	UBERON:0005343	71.66	gold quality
spleen	UBERON:0002106	69.92	gold quality
blood	UBERON:0000178	69.79	gold quality
apex of heart	UBERON:0002098	69.76	gold quality
vermiform appendix	UBERON:0001154	69.45	gold quality
ventricular zone	UBERON:0003053	68.88	gold quality
colonic epithelium	UBERON:0000397	68.44	silver quality
heart left ventricle	UBERON:0002084	67.03	gold quality
ganglionic eminence	UBERON:0004023	66.85	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.03	gold quality
right lung	UBERON:0002167	65.61	gold quality
calcaneal tendon	UBERON:0003701	64.92	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.61	gold quality
sural nerve	UBERON:0015488	64.57	gold quality
heart	UBERON:0000948	64.41	gold quality
gall bladder	UBERON:0002110	64.33	gold quality
adipose tissue	UBERON:0001013	63.55	gold quality
omental fat pad	UBERON:0010414	62.14	gold quality
prefrontal cortex	UBERON:0000451	61.97	gold quality
gastrocnemius	UBERON:0001388	61.83	gold quality
muscle of leg	UBERON:0001383	61.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.52

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology. (PMID:36129033)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.