SLC25A25-AS1

Summary

SLC25A25-AS1 (SLC25A25 antisense RNA 1, HGNC:27844) is a long non-coding RNA gene on chromosome 9q34.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27844
Approved symbol	SLC25A25-AS1
Name	SLC25A25 antisense RNA 1
Location	9q34.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	HRCEG
Ensembl gene	ENSG00000234771
Ensembl biotype	lncRNA
Entrez	100289019
RNAcentral	URS000075D94D — lncRNA, 3842 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000418747

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418747 — 5 exons

Exon	Start	End
ENSE00001658405	128113478	128114686
ENSE00001716775	128108581	128112649
ENSE00001791087	128117923	128118693
ENSE00003573477	128115074	128115289
ENSE00003574295	128117710	128117835

Expression profiles

Bgee: expression breadth ubiquitous, 193 present calls, max score 95.41.

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	95.41	gold quality
mucosa of transverse colon	UBERON:0004991	88.21	gold quality
colonic mucosa	UBERON:0000317	87.91	gold quality
mucosa of sigmoid colon	UBERON:0004993	87.65	gold quality
transverse colon	UBERON:0001157	83.10	gold quality
small intestine Peyer’s patch	UBERON:0003454	81.33	gold quality
jejunal mucosa	UBERON:0000399	81.31	gold quality
cerebellar hemisphere	UBERON:0002245	80.68	gold quality
right hemisphere of cerebellum	UBERON:0014890	80.62	gold quality
small intestine	UBERON:0002108	80.56	gold quality
cerebellar cortex	UBERON:0002129	80.54	gold quality
buccal mucosa cell	CL:0002336	80.31	gold quality
tendon of biceps brachii	UBERON:0008188	79.96	gold quality
rectum	UBERON:0001052	79.68	gold quality
duodenum	UBERON:0002114	79.63	gold quality
cerebellum	UBERON:0002037	79.56	gold quality
intestine	UBERON:0000160	79.41	gold quality
colon	UBERON:0001155	79.37	gold quality
large intestine	UBERON:0000059	79.34	gold quality
body of stomach	UBERON:0001161	78.90	gold quality
mucosa of stomach	UBERON:0001199	77.60	gold quality
stomach	UBERON:0000945	77.28	gold quality
granulocyte	CL:0000094	77.06	gold quality
metanephros cortex	UBERON:0010533	76.59	gold quality
colonic epithelium	UBERON:0000397	76.53	gold quality
apex of heart	UBERON:0002098	76.19	gold quality
body of pancreas	UBERON:0001150	76.17	gold quality
right uterine tube	UBERON:0001302	76.08	gold quality
medial globus pallidus	UBERON:0002477	75.96	gold quality
fallopian tube	UBERON:0003889	75.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.11

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Low SLC25A25-AS1 expression is associated with chemoresistance in colorectal cancer. (PMID:27553025)
• LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer. (PMID:31964588)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.