SLC25A34-AS1

Summary

SLC25A34-AS1 (SLC25A34 and TMEM82 antisense RNA 1, HGNC:53623) is a long non-coding RNA gene on chromosome 1p36.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53623
Approved symbol	SLC25A34-AS1
Name	SLC25A34 and TMEM82 antisense RNA 1
Location	1p36.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-169K16.4
Ensembl gene	ENSG00000224459
Ensembl biotype	lncRNA
Entrez	110806303
RNAcentral	URS0000BC43B5 — lncRNA, 644 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000418525, ENST00000763274, ENST00000763275, ENST00000763276, ENST00000763277

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418525 — 2 exons

Exon	Start	End
ENSE00004119235	15749430	15749896
ENSE00004119240	15739759	15740222

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 84.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1540 / max 22.7502, expressed in 62 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10468	0.0855	43
10467	0.0483	18
10466	0.0201	8

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.49	gold quality
ascending aorta	UBERON:0001496	83.66	gold quality
thoracic aorta	UBERON:0001515	83.52	gold quality
descending thoracic aorta	UBERON:0002345	81.16	gold quality
right coronary artery	UBERON:0001625	78.91	gold quality
left coronary artery	UBERON:0001626	76.45	gold quality
popliteal artery	UBERON:0002250	74.28	gold quality
tibial artery	UBERON:0007610	74.24	gold quality
gall bladder	UBERON:0002110	58.70	gold quality
ganglionic eminence	UBERON:0004023	57.48	gold quality
endocervix	UBERON:0000458	55.94	gold quality
monocyte	CL:0000576	55.77	gold quality
heart	UBERON:0000948	55.68	gold quality
placenta	UBERON:0001987	55.54	gold quality
multicellular organism	UBERON:0000468	53.25	gold quality
islet of Langerhans	UBERON:0000006	53.03	gold quality
liver	UBERON:0002107	52.84	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	52.52	gold quality
left uterine tube	UBERON:0001303	52.40	gold quality
prefrontal cortex	UBERON:0000451	52.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	51.35	gold quality
cortex of kidney	UBERON:0001225	50.54	gold quality
metanephros cortex	UBERON:0010533	50.35	gold quality
myometrium	UBERON:0001296	50.29	gold quality
kidney	UBERON:0002113	50.20	gold quality
adult mammalian kidney	UBERON:0000082	50.01	gold quality
blood	UBERON:0000178	48.87	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	48.31	gold quality
heart left ventricle	UBERON:0002084	48.23	gold quality
right ovary	UBERON:0002118	48.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.