SLC25A40

Summary

SLC25A40 (solute carrier family 25 member 40, HGNC:29680) is a protein-coding gene on chromosome 7q21.12, encoding Mitochondrial glutathione transporter SLC25A40 (Q8TBP6). Probable mitochondrial transporter required for glutathione import into mitochondria.

SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).

Source: NCBI Gene 55972 — RefSeq curated summary.

At a glance

• Clinical variants (ClinVar): 48 total
• MANE Select transcript: NM_018843

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:29680
Approved symbol	SLC25A40
Name	solute carrier family 25 member 40
Location	7q21.12
Locus type	gene with protein product
Status	Approved
Aliases	MCFP
Ensembl gene	ENSG00000075303
Ensembl biotype	protein_coding
OMIM	610821
Entrez	55972

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 17 protein_coding, 4 retained_intron, 3 nonsense_mediated_decay

ENST00000341119, ENST00000429674, ENST00000444363, ENST00000446236, ENST00000470328, ENST00000483810, ENST00000491499, ENST00000496348, ENST00000853625, ENST00000853626, ENST00000853627, ENST00000853628, ENST00000853629, ENST00000853630, ENST00000853631, ENST00000853632, ENST00000853633, ENST00000853634, ENST00000938988, ENST00000967380, ENST00000967381, ENST00000967382, ENST00000967383, ENST00000967384

RefSeq mRNA: 1 — MANE Select: NM_018843 NM_018843

CCDS: CCDS5610

Canonical transcript exons

ENST00000341119 — 12 exons

Exon	Start	End
ENSE00000701791	87856292	87856351
ENSE00000701918	87843754	87843863
ENSE00001016693	87876096	87876360
ENSE00001384244	87860572	87860640
ENSE00001929135	87833568	87836361
ENSE00003514743	87854204	87854310
ENSE00003527916	87847853	87847977
ENSE00003564795	87836730	87836810
ENSE00003571730	87849881	87849948
ENSE00003605972	87841633	87841714
ENSE00003662235	87846949	87847122
ENSE00003679989	87858631	87858751

Expression profiles

Bgee: expression breadth ubiquitous, 257 present calls, max score 92.71.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 20.6343 / max 140.3126, expressed in 1811 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
84736	9.5364	1778
84735	8.9573	1720
84731	2.1405	941

Top tissues by expression

291 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	92.71	gold quality
monocyte	CL:0000576	92.36	gold quality
mononuclear cell	CL:0000842	91.77	gold quality
leukocyte	CL:0000738	91.43	gold quality
epithelium of nasopharynx	UBERON:0001951	89.90	gold quality
lateral nuclear group of thalamus	UBERON:0002736	89.30	gold quality
endothelial cell	CL:0000115	87.82	gold quality
rectum	UBERON:0001052	87.70	gold quality
secondary oocyte	CL:0000655	87.09	gold quality
trabecular bone tissue	UBERON:0002483	86.68	gold quality
ventricular zone	UBERON:0003053	86.24	gold quality
mucosa of sigmoid colon	UBERON:0004993	86.24	gold quality
prefrontal cortex	UBERON:0000451	85.44	gold quality
skin of hip	UBERON:0001554	85.43	gold quality
bone marrow	UBERON:0002371	85.32	gold quality
postcentral gyrus	UBERON:0002581	85.30	gold quality
colonic mucosa	UBERON:0000317	85.10	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.83	gold quality
left ovary	UBERON:0002119	84.55	gold quality
heart right ventricle	UBERON:0002080	84.45	silver quality
right ovary	UBERON:0002118	84.27	gold quality
ganglionic eminence	UBERON:0004023	84.15	gold quality
endometrium	UBERON:0001295	84.13	gold quality
right adrenal gland cortex	UBERON:0035827	83.86	gold quality
superior frontal gyrus	UBERON:0002661	83.75	gold quality
blood	UBERON:0000178	83.62	gold quality
lymph node	UBERON:0000029	83.49	gold quality
tibial nerve	UBERON:0001323	83.47	gold quality
right adrenal gland	UBERON:0001233	83.43	gold quality
cortical plate	UBERON:0005343	83.43	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-MTAB-6142	no	65.77
E-ANND-3	no	4.72

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

114 targeting SLC25A40, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-5011-5P	100.00	83.46	5820
HSA-MIR-190A-3P	100.00	80.35	5520
HSA-MIR-1277-5P	100.00	73.95	5056
HSA-MIR-450A-1-3P	100.00	69.33	1837
HSA-MIR-3163	100.00	77.23	8605
HSA-MIR-30A-5P	100.00	76.31	3233
HSA-MIR-30B-5P	100.00	76.29	3248
HSA-MIR-30C-5P	100.00	76.29	3248
HSA-MIR-30D-5P	100.00	76.32	3233
HSA-MIR-30E-5P	100.00	76.32	3242
HSA-LET-7A-3P	100.00	74.03	3932
HSA-LET-7B-3P	100.00	74.08	3913
HSA-LET-7F-1-3P	100.00	74.02	3928
HSA-MIR-98-3P	100.00	74.08	3907
HSA-MIR-9-5P	100.00	72.28	2361
HSA-MIR-4282	99.99	75.36	6408
HSA-MIR-548C-3P	99.99	74.01	7587
HSA-MIR-4500	99.99	72.72	2367
HSA-MIR-548P	99.98	72.25	3784
HSA-MIR-551B-5P	99.96	71.28	3493
HSA-MIR-23A-3P	99.95	74.24	3163
HSA-MIR-23B-3P	99.95	74.24	3163
HSA-MIR-23C	99.95	73.92	3192
HSA-MIR-651-3P	99.94	73.48	5177
HSA-MIR-10523-5P	99.91	69.22	2038
HSA-MIR-5680	99.91	69.83	3421
HSA-MIR-8063	99.91	69.76	3146
HSA-MIR-95-5P	99.89	72.17	3973
HSA-MIR-4496	99.88	68.89	2236
HSA-MIR-3919	99.87	69.45	2489

Literature-anchored findings (GeneRIF, showing 3)

• Compares and contrasts all the known human SLC25A* genes and includes functional information. (PMID:23266187)
• Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. (PMID:24268658)
• SLC25A40 Facilitates Anticancer Drug Resistance in Human Leukemia K562 Cells. (PMID:37407483)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Slc25a40	ENSMUSG00000054099
rattus_norvegicus	Slc25a40	ENSRNOG00000022837

Paralogs (49): SLC25A13 (ENSG00000004864), SLC25A5 (ENSG00000005022), SLC25A39 (ENSG00000013306), SLC25A3 (ENSG00000075415), SLC25A43 (ENSG00000077713), SLC25A24 (ENSG00000085491), SLC25A1 (ENSG00000100075), SLC25A17 (ENSG00000100372), SLC25A14 (ENSG00000102078), SLC25A15 (ENSG00000102743), SLC25A11 (ENSG00000108528), UCP1 (ENSG00000109424), SLC25A36 (ENSG00000114120), SLC25A12 (ENSG00000115840), SLC25A2 (ENSG00000120329), SLC25A51 (ENSG00000122696), SLC25A16 (ENSG00000122912), SLC25A35 (ENSG00000125434), SLC25A19 (ENSG00000125454), SLC25A23 (ENSG00000125648), SLC25A47 (ENSG00000140107), SLC25A52 (ENSG00000141437), SLC25A38 (ENSG00000144659), SLC25A26 (ENSG00000144741), SLC25A48 (ENSG00000145832), SLC25A37 (ENSG00000147454), SLC25A25 (ENSG00000148339), SLC25A31 (ENSG00000151475), SLC25A4 (ENSG00000151729), SLC25A27 (ENSG00000153291), SLC25A28 (ENSG00000155287), SLC25A44 (ENSG00000160785), SLC25A45 (ENSG00000162241), SLC25A34 (ENSG00000162461), SLC25A32 (ENSG00000164933), SLC25A6 (ENSG00000169100), SLC25A33 (ENSG00000171612), SLC25A30 (ENSG00000174032), UCP3 (ENSG00000175564), UCP2 (ENSG00000175567)

Protein

Protein identifiers

Mitochondrial glutathione transporter SLC25A40 — Q8TBP6 (reviewed: Q8TBP6)

Alternative names: Mitochondrial carrier family protein, Solute carrier family 25 member 40

All UniProt accessions (3): Q8TBP6, F2Z3Q4, F8WEL8

UniProt curated annotations — full annotation on UniProt →

Function. Probable mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.

Subcellular location. Mitochondrion inner membrane.

Similarity. Belongs to the mitochondrial carrier (TC 2.A.29) family.

RefSeq proteins (1): NP_061331* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR002067	MCP	Family
IPR018108	MCP_transmembrane	Repeat
IPR023395	MCP_dom_sf	Homologous_superfamily
IPR045315	Mtm1-like	Family

Pfam: PF00153

Catalyzed reactions (Rhea), 1 shown:

• glutathione(in) = glutathione(out) (RHEA:74819)

UniProt features (15 total): transmembrane region 6, sequence variant 3, repeat 3, sequence conflict 2, chain 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8TBP6-F1	78.21	0.33

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 146 (showing top): GOBP_MYELOID_CELL_DIFFERENTIATION, WANG_CLIM2_TARGETS_UP, GOBP_MYELOID_CELL_HOMEOSTASIS, YAGI_AML_WITH_INV_16_TRANSLOCATION, GOBP_MYELOID_CELL_DEVELOPMENT, GOBP_MODIFIED_AMINO_ACID_TRANSPORT, GOBP_ERYTHROCYTE_HOMEOSTASIS, GOBP_MITOCHONDRIAL_TRANSPORT, GOBP_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT, BLALOCK_ALZHEIMERS_DISEASE_UP, GOBP_ORGANIC_ANION_TRANSPORT, GOBP_SULFUR_COMPOUND_TRANSPORT, GOCC_MITOCHONDRIAL_ENVELOPE, DODD_NASOPHARYNGEAL_CARCINOMA_UP, HNF1_C

GO Biological Process (5): erythrocyte development (GO:0048821), import into the mitochondrion (GO:0170036), glutathione transmembrane transport (GO:0034775), transmembrane transport (GO:0055085), mitochondrial transmembrane transport (GO:1990542)

GO Molecular Function (2): glutathione transmembrane transporter activity (GO:0034634), protein binding (GO:0005515)

GO Cellular Component (3): mitochondrion (GO:0005739), mitochondrial inner membrane (GO:0005743), membrane (GO:0016020)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
erythrocyte differentiation	1
myeloid cell development	1
intercellular transport	1
mitochondrial transmembrane transport	1
glutathione transport	1
tripeptide transmembrane transport	1
transport	1
cellular process	1
mitochondrial transport	1
transmembrane transport	1
glutathione transmembrane transport	1
tripeptide transmembrane transporter activity	1
modified amino acid transmembrane transporter activity	1
sulfur compound transmembrane transporter activity	1
binding	1
cytoplasm	1
intracellular membrane-bounded organelle	1
organelle inner membrane	1
mitochondrial membrane	1
cellular anatomical structure	1

Protein interactions and networks

STRING

766 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
SLC25A40	RUNDC3B	Q96NL0	662
SLC25A40	WDR44	Q5JSH3	541
SLC25A40	TMEM243	Q9BU79	500
SLC25A40	A0A087WVV2	A0A087WVV2	456
SLC25A40	SLC6A6	P31641	445
SLC25A40	CROT	Q9UKG9	443
SLC25A40	SEC61G	P38384	424
SLC25A40	DLGAP3	O95886	405
SLC25A40	FABP5	Q01469	392
SLC25A40	ADAM22	Q9P0K1	379
SLC25A40	ABCB1	P08183	366
SLC25A40	DMTF1	Q9Y222	358
SLC25A40	CNOT4	O95628	334
SLC25A40	SLC25A53	Q5H9E4	332
SLC25A40	FXYD3	Q14802	329

IntAct

49 interactions, top by confidence:

A	B	Type	Score
CFTR	ESYT2	psi-mi:“MI:0914”(association)	0.710
NME3	NME4	psi-mi:“MI:0914”(association)	0.640
FAM174A	BLTP3B	psi-mi:“MI:0914”(association)	0.530
TNFSF8	LGALS8	psi-mi:“MI:0914”(association)	0.530
APLNR	SLC33A1	psi-mi:“MI:0914”(association)	0.530
TMEM184A	SLC33A1	psi-mi:“MI:0914”(association)	0.530
SLC25A40	COL1A1	psi-mi:“MI:0915”(physical association)	0.500
ESR1	ESYT2	psi-mi:“MI:0914”(association)	0.350
SH2D3C	TMEM14DP	psi-mi:“MI:0914”(association)	0.350
M		psi-mi:“MI:0914”(association)	0.350
ATG16L1	ESYT2	psi-mi:“MI:0914”(association)	0.350
ATG16L1		psi-mi:“MI:0914”(association)	0.350
MGARP	BTAF1	psi-mi:“MI:0914”(association)	0.350
RAMP2	GXYLT2	psi-mi:“MI:0914”(association)	0.350
SLC25A40	POTEF	psi-mi:“MI:0914”(association)	0.350
SLC22A4	RTL8C	psi-mi:“MI:0914”(association)	0.350
FFAR1	SLC12A8	psi-mi:“MI:0914”(association)	0.350
GPR182	SLC12A8	psi-mi:“MI:0914”(association)	0.350
GP9	ESYT2	psi-mi:“MI:0914”(association)	0.350
GPR45	VWA8	psi-mi:“MI:0914”(association)	0.350
ASPH	POTEF	psi-mi:“MI:0914”(association)	0.350
OPALIN	FAM171A2	psi-mi:“MI:0914”(association)	0.350
MFSD4A	UBXN8	psi-mi:“MI:0914”(association)	0.350
SLC1A1	UBXN8	psi-mi:“MI:0914”(association)	0.350
AQP3	UBXN8	psi-mi:“MI:0914”(association)	0.350
NAAA	HAX1	psi-mi:“MI:0914”(association)	0.350
VIPR1	SLC33A1	psi-mi:“MI:0914”(association)	0.350
GPBAR1	SLC33A1	psi-mi:“MI:0914”(association)	0.350
BSG	TNPO2	psi-mi:“MI:0914”(association)	0.350

BioGRID (53): SLC25A40 (Affinity Capture-MS), SLC25A40 (Affinity Capture-MS), SLC25A40 (Affinity Capture-MS), SLC25A40 (Affinity Capture-MS), SLC25A40 (Proximity Label-MS), SLC25A40 (Proximity Label-MS), SLC25A40 (Proximity Label-MS), SLC25A40 (Proximity Label-MS), SLC25A40 (Proximity Label-MS), CHDH (Affinity Capture-MS), SLC25A40 (Affinity Capture-MS), SLC25A40 (Affinity Capture-MS), COL1A1 (Affinity Capture-MS), IST1 (Affinity Capture-MS), POTEF (Affinity Capture-MS)

ESM2 similar proteins: A0A0G2K309, A0A1D6N272, A3KPP4, G3XP90, G3YD89, O13844, P04575, P04633, P12234, P12242, P16036, P33303, Q08DK7, Q0VCH6, Q1LZB3, Q27257, Q29RM1, Q3KQZ1, Q3TZX3, Q505J6, Q58DS3, Q5HZE0, Q5IS35, Q5NVC1, Q5R7W2, Q5SWT3, Q6AYL0, Q6DFK2, Q6P036, Q6P316, Q7K566, Q8BGP6, Q8BL03, Q8BZ09, Q8N8R3, Q8TBP6, Q8VEM8, Q93XM7, Q99JD3, Q9BSK2

Diamond homologs: A0A1D6N272, A1DI57, A2A3V2, A2ASZ8, A2R5A0, A3LVX1, A4RF23, A5DIS9, A5DX39, A6RF73, A6SL61, A6ZV78, A7ER02, A7TDX5, B4FIJ0, K7VYZ9, O04619, O22261, O65023, O94370, P10861, P14271, P25874, P29518, P53257, P56500, P70406, Q05AQ3, Q08DK7, Q0CEN9, Q0UUH1, Q0V7M4, Q12251, Q1E7P0, Q1ECW7, Q29RM1, Q2HFL6, Q2UCW8, Q3SZK0, Q3ZBJ8

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

48 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	31
Likely benign	5
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

2603 predictions. Top by Δscore:

Variant	Effect	Δscore
7:87846943:TCCTA:T	donor_loss	1.0000
7:87846944:CCTA:C	donor_loss	1.0000
7:87846945:CTA:C	donor_loss	1.0000
7:87846946:TACCT:T	donor_loss	1.0000
7:87846947:A:T	donor_loss	1.0000
7:87846948:CCT:C	donor_loss	1.0000
7:87847024:T:A	donor_gain	1.0000
7:87847119:CCAA:C	acceptor_gain	1.0000
7:87847120:CAA:C	acceptor_gain	1.0000
7:87847120:CAAC:C	acceptor_gain	1.0000
7:87847123:C:CC	acceptor_gain	1.0000
7:87847126:A:AC	acceptor_gain	1.0000
7:87847133:CAAG:C	acceptor_gain	1.0000
7:87847134:A:T	acceptor_gain	1.0000
7:87847137:T:C	acceptor_gain	1.0000
7:87847137:T:TC	acceptor_gain	1.0000
7:87847846:TAC:T	donor_loss	1.0000
7:87847847:A:AC	donor_gain	1.0000
7:87847847:ACT:A	donor_loss	1.0000
7:87847848:C:CC	donor_gain	1.0000
7:87847848:C:G	donor_loss	1.0000
7:87847849:TCA:T	donor_loss	1.0000
7:87847851:A:AC	donor_gain	1.0000
7:87847851:ACAT:A	donor_gain	1.0000
7:87847852:C:CG	donor_gain	1.0000
7:87847852:CA:C	donor_gain	1.0000
7:87847852:CAT:C	donor_gain	1.0000
7:87847852:CATC:C	donor_gain	1.0000
7:87847852:CATCT:C	donor_gain	1.0000
7:87847973:TCACT:T	acceptor_gain	1.0000

AlphaMissense

2204 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
7:87836309:A:C	S319R	0.997
7:87836309:A:T	S319R	0.997
7:87836311:T:G	S319R	0.997
7:87836322:G:T	A315D	0.996
7:87847100:A:C	S160R	0.996
7:87847100:A:T	S160R	0.996
7:87847102:T:G	S160R	0.996
7:87841710:G:T	A249D	0.995
7:87847858:G:T	A151D	0.995
7:87846953:G:C	F209L	0.994
7:87846953:G:T	F209L	0.994
7:87846955:A:G	F209L	0.994
7:87843758:C:T	G246D	0.993
7:87846964:C:G	D206H	0.993
7:87849893:A:G	L107P	0.993
7:87849903:A:G	W104R	0.993
7:87849903:A:T	W104R	0.993
7:87841676:T:A	K260N	0.992
7:87841676:T:G	K260N	0.992
7:87841708:C:G	A250P	0.992
7:87849881:A:G	L111P	0.992
7:87858654:C:T	G25E	0.992
7:87836339:T:A	K309N	0.991
7:87836339:T:G	K309N	0.991
7:87846966:C:A	R205I	0.991
7:87856329:T:A	K40N	0.991
7:87856329:T:G	K40N	0.991
7:87858655:C:G	G25R	0.991
7:87858655:C:T	G25R	0.991
7:87836323:C:G	A315P	0.990

dbSNP variants (sampled 300 via entrez): RS1000021832 (7:87867704 G>A), RS1000090361 (7:87856550 G>A), RS1000161306 (7:87836325 C>G), RS1000161466 (7:87862369 G>A,T), RS1000203144 (7:87876477 C>T), RS1000219830 (7:87867972 C>G,T), RS1000324195 (7:87842910 T>C,G), RS1000377523 (7:87850047 T>G), RS1000395005 (7:87855716 T>C), RS1000425727 (7:87855407 C>A), RS1000438632 (7:87843330 T>TA), RS1000616551 (7:87836033 G>A,C), RS1000723832 (7:87865914 T>C), RS1000896219 (7:87850637 G>A), RS1000898149 (7:87863649 G>A,C)

Disease associations

OMIM: gene MIM:610821 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

GtoPdb / IUPHAR curated pharmacology

(IUPHAR/BPS Guide to Pharmacology — expert-curated)

Target class: transporter — SLC25 mitochondrial vitamin and co-factor carriers subfamily

CTD chemical–gene interactions

25 total (human), top 25 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	decreases expression, affects cotreatment, increases abundance	2
glycidyl methacrylate	decreases expression	1
quercitrin	decreases expression	1
cobaltous chloride	decreases expression	1
manganese chloride	affects cotreatment, decreases expression, increases abundance	1
abrine	decreases expression	1
Zoledronic Acid	increases expression	1
Acetaminophen	increases expression	1
Air Pollutants	decreases expression, increases abundance	1
Arsenic	affects cotreatment, decreases expression, increases abundance	1
Atrazine	increases expression	1
Benzo(a)pyrene	decreases methylation	1
Doxorubicin	decreases expression	1
Hydrogen Peroxide	affects expression	1
Ivermectin	decreases expression	1
Manganese	affects cotreatment, decreases expression, increases abundance	1
Methyl Methanesulfonate	increases expression	1
Rifampin	decreases expression	1
Silicon Dioxide	decreases expression	1
Tretinoin	increases expression	1
Valproic Acid	decreases methylation, increases expression	1
Aflatoxin B1	decreases methylation	1
Sodium Selenite	decreases expression	1
Copper Sulfate	decreases expression	1
Particulate Matter	decreases expression, increases abundance	1

Cellosaurus cell lines

7 cell lines: 6 cancer cell line, 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_B2FR	Abcam HeLa SLC25A40 KO	Cancer cell line	Female
CVCL_B3HA	Abcam HEK293T SLC25A40 KO	Transformed cell line	Female
CVCL_D4K9	HCT116-SLC25A40-KO-c3	Cancer cell line	Male
CVCL_D4KA	HCT116-SLC25A40-KO-c8	Cancer cell line	Male
CVCL_TM46	HAP1 SLC25A40 (-) 1	Cancer cell line	Male
CVCL_TM47	HAP1 SLC25A40 (-) 2	Cancer cell line	Male
CVCL_TM48	HAP1 SLC25A40 (-) 3	Cancer cell line	Male

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.