SLC2A1-DT

Summary

SLC2A1-DT (SLC2A1 divergent transcript, HGNC:44187) is a long non-coding RNA gene on chromosome 1p34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44187
Approved symbol	SLC2A1-DT
Name	SLC2A1 divergent transcript
Location	1p34.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227533
Ensembl biotype	lncRNA
Entrez	440584
RNAcentral	URS000075D721 — lncRNA, 1138 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 9 lncRNA, 1 retained_intron

ENST00000416689, ENST00000431759, ENST00000653200, ENST00000664148, ENST00000755356, ENST00000755357, ENST00000755358, ENST00000755359, ENST00000755360, ENST00000755361

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416689 — 3 exons

Exon	Start	End
ENSE00001777132	42970249	42970394
ENSE00004104340	42973974	42976428
ENSE00004104341	42959032	42959577

Expression profiles

Bgee: expression breadth ubiquitous, 168 present calls, max score 84.47.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.2427 / max 149.6492, expressed in 974 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
2483	1.4873	674
2484	0.9176	439
2485	0.8378	356

Top tissues by expression

223 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	84.47	gold quality
vena cava	UBERON:0004087	82.21	silver quality
lateral globus pallidus	UBERON:0002476	80.44	gold quality
nipple	UBERON:0002030	79.83	silver quality
pharyngeal mucosa	UBERON:0000355	79.35	silver quality
dorsal plus ventral thalamus	UBERON:0001897	79.10	silver quality
cerebellar vermis	UBERON:0004720	78.95	gold quality
superior surface of tongue	UBERON:0007371	78.84	silver quality
trachea	UBERON:0003126	78.43	gold quality
substantia nigra pars reticulata	UBERON:0001966	78.42	silver quality
pericardium	UBERON:0002407	78.32	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	78.28	gold quality
lateral nuclear group of thalamus	UBERON:0002736	78.27	silver quality
nasal cavity epithelium	UBERON:0005384	78.22	gold quality
pons	UBERON:0000988	78.05	silver quality
substantia nigra pars compacta	UBERON:0001965	78.02	silver quality
thymus	UBERON:0002370	77.88	gold quality
renal medulla	UBERON:0000362	77.08	silver quality
synovial joint	UBERON:0002217	76.92	silver quality
penis	UBERON:0000989	76.37	silver quality
sural nerve	UBERON:0015488	75.85	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.93	gold quality
layer of synovial tissue	UBERON:0007616	74.80	silver quality
deltoid	UBERON:0001476	72.71	gold quality
quadriceps femoris	UBERON:0001377	72.22	gold quality
vastus lateralis	UBERON:0001379	72.03	gold quality
superficial temporal artery	UBERON:0001614	71.47	gold quality
biceps brachii	UBERON:0001507	70.96	gold quality
skeletal muscle tissue	UBERON:0001134	70.87	gold quality
popliteal artery	UBERON:0002250	69.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.23

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Long noncoding RNA SLC2A1-AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway. (PMID:32174012)
• TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation. (PMID:33580997)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.