SLC37A2

Summary

SLC37A2 (solute carrier family 37 member 2, HGNC:20644) is a protein-coding gene on chromosome 11q24.2, encoding Glucose-6-phosphate exchanger SLC37A2 (Q8TED4). Inorganic phosphate and glucose-6-phosphate antiporter.

Enables glucose 6-phosphate:phosphate antiporter activity. Involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Located in endoplasmic reticulum membrane.

Source: NCBI Gene 219855 — RefSeq curated summary.

At a glance

• GWAS associations: 2
• Clinical variants (ClinVar): 90 total
• MANE Select transcript: NM_001145290

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20644
Approved symbol	SLC37A2
Name	solute carrier family 37 member 2
Location	11q24.2
Locus type	gene with protein product
Status	Approved
Aliases	FLJ00171, SPX2
Ensembl gene	ENSG00000134955
Ensembl biotype	protein_coding
OMIM	619136
Entrez	219855

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 4 protein_coding, 2 protein_coding_CDS_not_defined, 1 retained_intron

ENST00000308074, ENST00000354617, ENST00000403796, ENST00000525837, ENST00000526405, ENST00000532000, ENST00000964167

RefSeq mRNA: 2 — MANE Select: NM_001145290 NM_001145290, NM_198277

CCDS: CCDS31714, CCDS44757

Canonical transcript exons

ENST00000403796 — 18 exons

Exon	Start	End
ENSE00000994863	125084234	125084319
ENSE00002185255	125063305	125063426
ENSE00003485350	125079112	125079247
ENSE00003491859	125085395	125085473
ENSE00003500244	125079684	125079760
ENSE00003502661	125088119	125090516
ENSE00003517706	125077450	125077528
ENSE00003560674	125085066	125085139
ENSE00003573745	125083815	125083877
ENSE00003588964	125084825	125084873
ENSE00003626209	125082244	125082334
ENSE00003628185	125080614	125080780
ENSE00003641030	125076757	125076838
ENSE00003675059	125085954	125086018
ENSE00003687249	125081421	125081458
ENSE00003688651	125077230	125077323
ENSE00003689212	125085577	125085674
ENSE00003691583	125081754	125081906

Expression profiles

Bgee: expression breadth ubiquitous, 199 present calls, max score 94.98.

FANTOM5 (CAGE): breadth broad, TPM avg 9.7923 / max 265.7821, expressed in 738 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
117430	6.5905	558
117428	1.3331	237
117427	1.2332	265
117429	0.3182	138
117434	0.2053	107
117426	0.1119	32

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right adrenal gland	UBERON:0001233	94.98	gold quality
left adrenal gland	UBERON:0001234	94.64	gold quality
right adrenal gland cortex	UBERON:0035827	94.23	gold quality
left adrenal gland cortex	UBERON:0035825	93.79	gold quality
adrenal cortex	UBERON:0001235	93.06	gold quality
lower esophagus mucosa	UBERON:0035834	92.74	gold quality
adrenal gland	UBERON:0002369	91.96	gold quality
skin of leg	UBERON:0001511	91.35	gold quality
monocyte	CL:0000576	90.92	gold quality
leukocyte	CL:0000738	90.87	gold quality
upper arm skin	UBERON:0004263	90.78	gold quality
granulocyte	CL:0000094	90.08	gold quality
parotid gland	UBERON:0001831	89.82	gold quality
saliva-secreting gland	UBERON:0001044	89.69	gold quality
cardiac muscle of right atrium	UBERON:0003379	89.28	gold quality
minor salivary gland	UBERON:0001830	89.03	gold quality
skin of abdomen	UBERON:0001416	88.61	gold quality
zone of skin	UBERON:0000014	88.18	gold quality
nasal cavity epithelium	UBERON:0005384	87.95	silver quality
kidney epithelium	UBERON:0004819	87.58	gold quality
mouth mucosa	UBERON:0003729	87.49	gold quality
ileal mucosa	UBERON:0000331	87.05	gold quality
spleen	UBERON:0002106	86.61	gold quality
esophagus mucosa	UBERON:0002469	86.28	gold quality
vermiform appendix	UBERON:0001154	86.10	gold quality
vena cava	UBERON:0004087	85.67	silver quality
caecum	UBERON:0001153	84.82	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	81.41	gold quality
rectum	UBERON:0001052	81.10	gold quality
penis	UBERON:0000989	80.86	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-CURD-112	yes	16.77
E-ANND-3	yes	8.89
E-MTAB-5061	no	3.54

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

78 targeting SLC37A2, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4747-5P	100.00	67.90	2681
HSA-MIR-5196-5P	100.00	67.98	2761
HSA-MIR-4692	100.00	67.32	2066
HSA-LET-7A-3P	100.00	74.03	3932
HSA-LET-7B-3P	100.00	74.08	3913
HSA-LET-7F-1-3P	100.00	74.02	3928
HSA-MIR-98-3P	100.00	74.08	3907
HSA-MIR-4514	99.99	67.10	1870
HSA-MIR-4650-5P	99.98	64.69	999
HSA-MIR-9-3P	99.96	70.88	2068
HSA-MIR-381-3P	99.93	71.87	2854
HSA-MIR-300	99.92	71.76	2856
HSA-MIR-6768-5P	99.92	67.36	1942
HSA-MIR-345-3P	99.89	70.23	1421
HSA-MIR-95-5P	99.89	72.17	3973
HSA-MIR-4492	99.87	68.25	3611
HSA-MIR-4319	99.76	69.83	2586
HSA-MIR-6763-5P	99.76	64.68	1767
HSA-MIR-4306	99.72	70.50	3630
HSA-MIR-6752-3P	99.72	66.71	1587
HSA-MIR-378G	99.71	64.90	1106
HSA-MIR-5004-5P	99.68	66.63	1294
HSA-MIR-646	99.68	67.84	1645
HSA-MIR-670-5P	99.67	69.94	1565
HSA-MIR-4804-3P	99.65	67.78	866
HSA-MIR-762	99.58	66.61	1994
HSA-MIR-451B	99.55	68.28	1380
HSA-MIR-4498	99.47	67.42	2360
HSA-MIR-4797-5P	99.39	68.01	1354
HSA-MIR-5580-5P	99.38	66.96	1139

Literature-anchored findings (GeneRIF, showing 2)

• Data show that SLC37A1 and SLC37A2 are endoplasmic reticulum associated, P(i)-linked antiporters, that can transport glucose-6-phosphate. (PMID:21949678)
• Using both living fish embryos and mammalian macrophages, we show that processing depends on the shrinkage and packaging of phagosomes into a unique cellular compartment, the gastrosome, with distinct molecular and ultra-structural characteristics. Loss of the transporter Slc37a2 blocks phagosomal shrinkage, resulting in the expansion of the gastrosome and the dramatic bloating of the cell. (PMID:30880002)

Cross-species orthologs

37 orthologs

Organism	Symbol	Gene ID
danio_rerio	slc37a2	ENSDARG00000023394
mus_musculus	Slc37a2	ENSMUSG00000032122
drosophila_melanogaster	dmGlut	FBGN0010497
drosophila_melanogaster	Picot	FBGN0024315
drosophila_melanogaster	CG9254	FBGN0028513
drosophila_melanogaster	CG6978	FBGN0029727
drosophila_melanogaster	VGlut	FBGN0031424
drosophila_melanogaster	MFS16	FBGN0034611
caenorhabditis_elegans		WBGENE00001135
caenorhabditis_elegans		WBGENE00007669
caenorhabditis_elegans		WBGENE00008677
caenorhabditis_elegans		WBGENE00010755
caenorhabditis_elegans		WBGENE00010931
caenorhabditis_elegans		WBGENE00011185
caenorhabditis_elegans		WBGENE00011556
caenorhabditis_elegans		WBGENE00012443
caenorhabditis_elegans		WBGENE00015271
caenorhabditis_elegans		WBGENE00015272
caenorhabditis_elegans		WBGENE00016003
caenorhabditis_elegans		WBGENE00018429
caenorhabditis_elegans		WBGENE00018918
caenorhabditis_elegans		WBGENE00018920
caenorhabditis_elegans		WBGENE00019187
caenorhabditis_elegans		WBGENE00019655
caenorhabditis_elegans		WBGENE00020583
caenorhabditis_elegans		WBGENE00020584
caenorhabditis_elegans		WBGENE00020697
caenorhabditis_elegans		WBGENE00020698
caenorhabditis_elegans		WBGENE00020699
caenorhabditis_elegans		WBGENE00020700
caenorhabditis_elegans		WBGENE00021157
caenorhabditis_elegans		WBGENE00021158
caenorhabditis_elegans		WBGENE00021219
caenorhabditis_elegans		WBGENE00021220
caenorhabditis_elegans		WBGENE00021223
caenorhabditis_elegans		WBGENE00021226
caenorhabditis_elegans		WBGENE00302978

Paralogs (12): SLC17A6 (ENSG00000091664), SLC17A9 (ENSG00000101194), SLC17A7 (ENSG00000104888), SLC17A2 (ENSG00000112337), SLC17A5 (ENSG00000119899), SLC17A3 (ENSG00000124564), SLC17A1 (ENSG00000124568), SLC37A4 (ENSG00000137700), SLC17A4 (ENSG00000146039), SLC37A3 (ENSG00000157800), SLC37A1 (ENSG00000160190), SLC17A8 (ENSG00000179520)

Protein

Protein identifiers

Glucose-6-phosphate exchanger SLC37A2 — Q8TED4 (reviewed: Q8TED4)

Alternative names: Solute carrier family 37 member 2

All UniProt accessions (2): Q8TED4, E9PRJ4

UniProt curated annotations — full annotation on UniProt →

Function. Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.

Subcellular location. Endoplasmic reticulum membrane.

Tissue specificity. Detected in intestine and pancreas. Lower expression is also detected in liver and kidney.

Activity regulation. Inhibited by vanadate but not by chlorogenic acid.

Similarity. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.

Isoforms (4)

UniProt ID	Names	Canonical?
Q8TED4-1	1	yes
Q8TED4-2	2
Q8TED4-3	3
Q8TED4-4	4

RefSeq proteins (2): NP_001138762, NP_938018 (=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR000849	Sugar_P_transporter	Family
IPR011701	MFS	Family
IPR020846	MFS_dom	Domain
IPR036259	MFS_trans_sf	Homologous_superfamily
IPR044740	SLC37A1_2	Family

Pfam: PF07690

Catalyzed reactions (Rhea), 1 shown:

• D-glucose 6-phosphate(in) + phosphate(out) = D-glucose 6-phosphate(out) + phosphate(in) (RHEA:71535)

UniProt features (24 total): transmembrane region 12, splice variant 4, glycosylation site 3, sequence variant 2, chain 1, region of interest 1, sequence conflict 1

Structure

Experimental structures (PDB)

4 structures.

PDB	Method	Resolution (Å)
9UCM	ELECTRON MICROSCOPY	3.2
9UDW	ELECTRON MICROSCOPY	3.5
9UDV	ELECTRON MICROSCOPY	3.6
9UDX	ELECTRON MICROSCOPY	3.7

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8TED4-F1	84.05	0.54

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Glycosylation sites (3): 53, 62, 68

Function

Pathways and Gene Ontology

Reactome pathways

1 pathways

ID	Pathway
R-HSA-70263	Gluconeogenesis

MSigDB gene sets: 191 (showing top): GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP, GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP, GOBP_INORGANIC_ANION_TRANSPORT, TGACCTY_ERR1_Q2, GOBP_ORGANOPHOSPHATE_ESTER_TRANSPORT, GOBP_PHOSPHATE_ION_TRANSPORT, GOBP_ORGANIC_ANION_TRANSPORT, REACTOME_GLUCONEOGENESIS, AML1_01, HAMAI_APOPTOSIS_VIA_TRAIL_DN, GOBP_CARBOHYDRATE_DERIVATIVE_TRANSPORT, GOBP_TRANSMEMBRANE_TRANSPORT, TGACCTTG_SF1_Q6, REACTOME_METABOLISM_OF_CARBOHYDRATES_AND_CARBOHYDRATE_DERIVATIVES, GOCC_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK

GO Biological Process (3): glucose-6-phosphate transport (GO:0015760), phosphate ion transmembrane transport (GO:0035435), transmembrane transport (GO:0055085)

GO Molecular Function (3): glucose 6-phosphate:phosphate antiporter activity (GO:0061513), antiporter activity (GO:0015297), transmembrane transporter activity (GO:0022857)

GO Cellular Component (5): endoplasmic reticulum membrane (GO:0005789), extracellular exosome (GO:0070062), endoplasmic reticulum (GO:0005783), membrane (GO:0016020), organelle membrane (GO:0031090)

Reactome top-level categories

Rollup of top-1 pathways:

Category	Pathways
Glucose metabolism	1

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
transmembrane transport	2
hexose phosphate transport	1
phosphate ion transport	1
transport	1
cellular process	1
glucose-6-phosphate transmembrane transporter activity	1
hexose-phosphate:phosphate antiporter activity	1
secondary active transmembrane transporter activity	1
transporter activity	1
organelle membrane	1
nuclear outer membrane-endoplasmic reticulum membrane network	1
endoplasmic reticulum subcompartment	1
extracellular vesicle	1
cytoplasm	1
endomembrane system	1
intracellular membrane-bounded organelle	1
cellular anatomical structure	1
membrane	1
membrane-bounded organelle	1

Protein interactions and networks

STRING

792 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
SLC37A2	FNIP1	Q8TF40	459
SLC37A2	PKNOX2	Q96KN3	429
SLC37A2	RALGPS2	Q86X27	387
SLC37A2	ARHGEF1	Q92888	387
SLC37A2	SLK	Q9H2G2	353
SLC37A2	ARHGEF11	O15085	336
SLC37A2	PGBD4	Q96DM1	325
SLC37A2	TMEM217	Q8N7C4	324
SLC37A2	ESRP1	Q6NXG1	323
SLC37A2	PTPRM	P28827	314
SLC37A2	FXYD4	P59646	313
SLC37A2	NBEA	Q8NFP9	312
SLC37A2	SCRIB	Q14160	299
SLC37A2	SPATA2L	Q8IUW3	287
SLC37A2	VSTM4	Q8IW00	286

IntAct

3 interactions, top by confidence:

A	B	Type	Score
KLHL22	TRAV18	psi-mi:“MI:0914”(association)	0.350
SLC37A2	WWP2	psi-mi:“MI:0914”(association)	0.350

BioGRID (94): SLC37A2 (Affinity Capture-MS), ABCA3 (Affinity Capture-MS), ABCB6 (Affinity Capture-MS), ACSL4 (Affinity Capture-MS), ACVR1B (Affinity Capture-MS), ADCY3 (Affinity Capture-MS), AGPAT2 (Affinity Capture-MS), ANKRD13A (Affinity Capture-MS), ANKRD13D (Affinity Capture-MS), ATP13A2 (Affinity Capture-MS), ATP8A1 (Affinity Capture-MS), BMPR1A (Affinity Capture-MS), BROX (Affinity Capture-MS), CA2 (Affinity Capture-MS), CBR1 (Affinity Capture-MS)

ESM2 similar proteins: A0A3Q2HW92, A6NDV4, A6NFX1, D2HKB0, D3ZVU9, F1NCD6, F1NJ67, F1PZV2, O09014, Q0IHM1, Q0P5M9, Q14728, Q14CX5, Q3T9M1, Q3U481, Q3UGX3, Q58CT4, Q58CV5, Q5JZQ7, Q5VTY9, Q66H95, Q6AY78, Q6NUT3, Q6PDE8, Q6UXD7, Q6W5G4, Q6ZMD2, Q7RTT9, Q80T22, Q8BFQ6, Q8CE47, Q8IVW8, Q8N697, Q8NA29, Q8R139, Q8TED4, Q8VCW4, Q8VCY8, Q8WUG5, Q91VM4

Diamond homologs: O23596, P57057, Q17QZ3, Q3TIT8, Q58CV5, Q5F3N0, Q5M7K3, Q640L2, Q7SY29, Q8AVC3, Q8NCC5, Q8R070, Q8TED4, Q9C5L3, Q9SA71, Q9SB41, Q9SL56, Q9WU81, P42205, P9WG86, P9WG87

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

90 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	60
Likely benign	7
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

2538 predictions. Top by Δscore:

Variant	Effect	Δscore
11:125076752:TGCA:T	acceptor_loss	1.0000
11:125076753:GCA:G	acceptor_loss	1.0000
11:125076755:A:AG	acceptor_gain	1.0000
11:125076756:G:GG	acceptor_gain	1.0000
11:125076817:G:GT	donor_gain	1.0000
11:125076836:AAGGT:A	donor_loss	1.0000
11:125076839:GTGA:G	donor_loss	1.0000
11:125076840:T:G	donor_loss	1.0000
11:125077225:TCCA:T	acceptor_loss	1.0000
11:125077226:CCA:C	acceptor_loss	1.0000
11:125077227:CA:C	acceptor_loss	1.0000
11:125077228:A:AG	acceptor_gain	1.0000
11:125077229:G:A	acceptor_loss	1.0000
11:125077229:G:GG	acceptor_gain	1.0000
11:125077229:GA:G	acceptor_gain	1.0000
11:125077229:GAGCC:G	acceptor_gain	1.0000
11:125077322:TGGTA:T	donor_loss	1.0000
11:125077324:G:GG	donor_gain	1.0000
11:125077324:GTA:G	donor_loss	1.0000
11:125077325:T:G	donor_loss	1.0000
11:125077438:A:AG	acceptor_gain	1.0000
11:125077438:ATCT:A	acceptor_gain	1.0000
11:125077439:T:G	acceptor_gain	1.0000
11:125077441:T:A	acceptor_gain	1.0000
11:125077446:TCA:T	acceptor_loss	1.0000
11:125077448:A:AG	acceptor_gain	1.0000
11:125077448:A:C	acceptor_loss	1.0000
11:125077449:G:GC	acceptor_gain	1.0000
11:125077449:GA:G	acceptor_gain	1.0000
11:125077449:GAC:G	acceptor_gain	1.0000

AlphaMissense

3284 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
11:125080636:T:A	W184R	1.000
11:125080636:T:C	W184R	1.000
11:125082269:T:C	L304P	1.000
11:125076816:G:T	R40M	0.999
11:125076827:A:C	S44R	0.999
11:125076829:T:A	S44R	0.999
11:125076829:T:G	S44R	0.999
11:125077494:T:C	F94L	0.999
11:125077496:C:A	F94L	0.999
11:125077496:C:G	F94L	0.999
11:125079693:G:A	G154R	0.999
11:125079693:G:C	G154R	0.999
11:125079694:G:A	G154E	0.999
11:125079714:T:A	W161R	0.999
11:125079714:T:C	W161R	0.999
11:125079716:G:C	W161C	0.999
11:125079716:G:T	W161C	0.999
11:125080619:G:A	G178E	0.999
11:125080630:G:C	G182R	0.999
11:125080657:G:C	G191R	0.999
11:125080658:G:A	G191D	0.999
11:125080658:G:T	G191V	0.999
11:125080662:C:A	N192K	0.999
11:125080662:C:G	N192K	0.999
11:125080669:G:C	G195R	0.999
11:125080705:T:A	W207R	0.999
11:125080705:T:C	W207R	0.999
11:125080707:G:C	W207C	0.999
11:125080707:G:T	W207C	0.999
11:125082256:T:C	F300L	0.999

dbSNP variants (sampled 300 via entrez): RS1000043552 (11:125090907 G>C), RS1000171968 (11:125072333 C>T), RS1000241969 (11:125087431 C>T), RS1000253636 (11:125075926 C>T), RS1000284828 (11:125076092 A>G,T), RS1000369880 (11:125082082 G>A), RS1000422192 (11:125082463 T>A,C), RS1000581577 (11:125064288 G>A,T), RS1000723031 (11:125066657 A>G), RS1000808860 (11:125077210 A>G), RS1000847089 (11:125086501 G>A), RS1001071904 (11:125066377 C>T), RS1001177763 (11:125070793 A>G), RS1001549313 (11:125063274 A>AT), RS1001580370 (11:125063091 G>C,T)

Disease associations

OMIM: gene MIM:619136 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

2 associations (top):

Study	Trait	p-value
GCST002861_2	Breast cancer (survival)	1.000000e-09
GCST006979_233	Heel bone mineral density	7.000000e-10

EFO canonical traits (2, from GWAS)

EFO ID	Trait name
EFO:0000714	survival time
EFO:0009270	heel bone mineral density

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

GtoPdb / IUPHAR curated pharmacology

(IUPHAR/BPS Guide to Pharmacology — expert-curated)

Target class: transporter — SLC37 family of phosphosugar/phosphate exchangers

CTD chemical–gene interactions

37 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Benzo(a)pyrene	affects methylation, increases expression, increases methylation	4
Tetrachlorodibenzodioxin	increases expression	3
Tobacco Smoke Pollution	increases expression, affects expression, decreases expression	3
sodium arsenite	decreases expression, affects cotreatment, increases abundance, increases expression	2
perfluorooctane sulfonic acid	increases expression	2
Arsenic	increases abundance, affects cotreatment, increases expression, decreases expression	2
Cadmium Chloride	decreases expression, increases abundance, increases expression	2
Particulate Matter	increases expression, increases abundance	2
aristolochic acid I	increases expression	1
methyleugenol	increases expression	1
lead acetate	increases expression	1
sodium arsenate	increases abundance, decreases expression	1
butyraldehyde	increases expression	1
diallyl trisulfide	increases expression	1
pentanal	decreases expression	1
CGP 52608	affects binding, increases reaction	1
perfluoro-n-nonanoic acid	increases expression	1
bisphenol S	increases expression	1
Air Pollutants	increases abundance, increases expression	1
Air Pollutants, Occupational	decreases expression	1
Cadmium	decreases expression, increases abundance	1
Hydrogen Peroxide	affects expression	1
Nickel	decreases expression	1
Nicotine	increases expression	1
Phenobarbital	affects expression	1
Progesterone	decreases expression	1
Quercetin	increases expression	1
Smoke	increases expression	1
Thiram	decreases expression	1
Urethane	decreases expression	1

Cellosaurus cell lines

2 cell lines: 2 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_D4F8	1321N1-SLC37A2-KO-c3	Cancer cell line	Male
CVCL_D4F9	1321N1-SLC37A2-KO-c7	Cancer cell line	Male

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.