SLC44A3-AS1

Summary

SLC44A3-AS1 (SLC44A3 antisense RNA 1, HGNC:49057) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (transcribed_processed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49057
Approved symbol	SLC44A3-AS1
Name	SLC44A3 antisense RNA 1
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224081
Ensembl biotype	transcribed_processed_pseudogene
Entrez	101928079
RNAcentral	URS0000D5B53B — lncRNA, 1282 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_processed_pseudogene

ENST00000424505

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424505 — 2 exons

Exon	Start	End
ENSE00001652685	94672918	94673294
ENSE00001671872	94673927	94674161

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 85.28.

FANTOM5 (CAGE): breadth broad, TPM avg 1.4230 / max 49.0735, expressed in 631 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13415	0.8164	454
13413	0.3980	193
13414	0.1546	67
13407	0.0540	18

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	85.28	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.39	gold quality
metanephros cortex	UBERON:0010533	82.83	gold quality
mucosa of transverse colon	UBERON:0004991	82.56	gold quality
body of pancreas	UBERON:0001150	82.47	gold quality
adenohypophysis	UBERON:0002196	82.32	gold quality
transverse colon	UBERON:0001157	81.29	gold quality
rectum	UBERON:0001052	80.98	gold quality
minor salivary gland	UBERON:0001830	80.83	gold quality
colonic epithelium	UBERON:0000397	80.21	gold quality
pituitary gland	UBERON:0000007	79.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.52	gold quality
epithelial cell of pancreas	CL:0000083	79.51	gold quality
pancreas	UBERON:0001264	79.50	gold quality
right adrenal gland	UBERON:0001233	78.81	gold quality
right uterine tube	UBERON:0001302	77.79	gold quality
gall bladder	UBERON:0002110	77.76	gold quality
left adrenal gland	UBERON:0001234	77.39	gold quality
mouth mucosa	UBERON:0003729	76.97	gold quality
right adrenal gland cortex	UBERON:0035827	76.91	gold quality
small intestine Peyer’s patch	UBERON:0003454	76.88	gold quality
left adrenal gland cortex	UBERON:0035825	76.79	gold quality
adrenal gland	UBERON:0002369	76.30	gold quality
adult mammalian kidney	UBERON:0000082	76.20	gold quality
body of stomach	UBERON:0001161	76.07	gold quality
saliva-secreting gland	UBERON:0001044	76.02	gold quality
islet of Langerhans	UBERON:0000006	75.86	gold quality
cortex of kidney	UBERON:0001225	75.77	gold quality
adrenal cortex	UBERON:0001235	75.51	gold quality
small intestine	UBERON:0002108	74.91	gold quality

Single-cell (SCXA)

Detected in 4 experiment(s), a significant marker in 4.

Experiment	Marker?	Max mean expression
E-MTAB-8495	yes	265.05
E-MTAB-10018	yes	199.17
E-GEOD-125970	yes	18.37
E-ANND-3	yes	5.40

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Role of SLC44A3-AS1 Enhancer RNA in Esophageal Cancer Prognosis. (PMID:37691355)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.