SLC5A4-AS1

Summary

SLC5A4-AS1 (SLC5A4 antisense RNA 1, HGNC:53163) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53163
Approved symbol	SLC5A4-AS1
Name	SLC5A4 antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP1-90G24.10
Ensembl gene	ENSG00000242082
Ensembl biotype	lncRNA
Entrez	110806273
RNAcentral	URS0000BC45B2 — lncRNA, 4825 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000434942, ENST00000452181

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434942 — 5 exons

Exon	Start	End
ENSE00001654069	32207136	32207276
ENSE00001689784	32269357	32273615
ENSE00001752562	32268288	32268579
ENSE00003841231	32205165	32205247
ENSE00003848184	32229090	32229372

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 63.75.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0405 / max 54.2742, expressed in 336 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
191866	0.9832	327
191865	0.0573	20

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	63.75	gold quality
bone marrow cell	CL:0002092	63.42	silver quality
bone marrow	UBERON:0002371	61.03	gold quality
ventricular zone	UBERON:0003053	60.70	gold quality
primary visual cortex	UBERON:0002436	60.52	gold quality
prostate gland	UBERON:0002367	60.30	gold quality
superior frontal gyrus	UBERON:0002661	59.92	gold quality
ganglionic eminence	UBERON:0004023	59.72	gold quality
prefrontal cortex	UBERON:0000451	58.24	gold quality
frontal cortex	UBERON:0001870	57.04	gold quality
cortex of kidney	UBERON:0001225	56.81	gold quality
islet of Langerhans	UBERON:0000006	56.78	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.41	gold quality
leukocyte	CL:0000738	56.39	gold quality
monocyte	CL:0000576	56.15	gold quality
cerebral cortex	UBERON:0000956	55.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.43	gold quality
right frontal lobe	UBERON:0002810	55.21	gold quality
lymph node	UBERON:0000029	54.97	gold quality
blood	UBERON:0000178	54.87	gold quality
tonsil	UBERON:0002372	54.22	gold quality
pancreas	UBERON:0001264	54.06	gold quality
granulocyte	CL:0000094	53.89	gold quality
anterior cingulate cortex	UBERON:0009835	53.77	gold quality
cerebellum	UBERON:0002037	53.75	gold quality
cerebellar cortex	UBERON:0002129	53.61	gold quality
cerebellar hemisphere	UBERON:0002245	53.52	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.80	gold quality
duodenum	UBERON:0002114	52.26	gold quality
brain	UBERON:0000955	51.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.