SLC60A1-AS1

Summary

SLC60A1-AS1 (SLC60A1 antisense RNA 1, HGNC:27632) is a long non-coding RNA gene on chromosome 1q32.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27632
Approved symbol	SLC60A1-AS1
Name	SLC60A1 antisense RNA 1
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	284578
RNAcentral	URS0000CCE071 — lncRNA, 2985 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA MFSD4A-AS1 promotes lymphangiogenesis and lymphatic metastasis of papillary thyroid cancer. (PMID:36606578)

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 3 (showing top): FAN_EMBRYONIC_CTX_BIG_GROUPS_CAJAL_RETZIUS, GSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_DN, chr1q32

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

10 predictions. Top by Δscore:

Variant	Effect	Δscore
1:205569295:AGGAC:A	donor_gain	1.0000
1:205569296:GGAC:G	donor_gain	1.0000
1:205569296:GGACG:G	donor_gain	1.0000
1:205569283:G:T	donor_gain	0.7100
1:205569283:G:GT	donor_gain	0.5200
1:205569136:A:T	donor_gain	0.4500
1:205569150:C:G	donor_gain	0.3500
1:205569253:C:G	donor_gain	0.3500
1:205569202:C:A	donor_gain	0.2800
1:205569236:T:TA	donor_gain	0.2000

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000111969 (1:205565390 A>C), RS1000340105 (1:205558293 C>A,G), RS1000409872 (1:205558597 G>A,T), RS1000544589 (1:205568036 G>A), RS1000986772 (1:205561019 G>A,C), RS1001084088 (1:205554188 A>G), RS1001291185 (1:205566312 G>A), RS1001318149 (1:205559474 CT>C), RS1001347887 (1:205559795 A>AAAG), RS1001425250 (1:205566565 A>G), RS1001839378 (1:205558730 C>T), RS1002562357 (1:205565157 A>C,G), RS1002854786 (1:205565343 C>A), RS1002961741 (1:205567642 G>A), RS1003095619 (1:205567877 G>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Dihydrotestosterone	increases expression	1
Triclosan	increases expression	1
Aflatoxin B1	decreases methylation	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.