SLC6A1-AS1

Summary

SLC6A1-AS1 (SLC6A1 antisense RNA 1, HGNC:40546) is a long non-coding RNA gene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40546
Approved symbol	SLC6A1-AS1
Name	SLC6A1 antisense RNA 1
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232287
Ensembl biotype	lncRNA
Entrez	100874090
RNAcentral	URS000047B0CD — lncRNA, 584 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000414969

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414969 — 3 exons

Exon	Start	End
ENSE00001717407	11006098	11006388
ENSE00001788387	11007192	11007379
ENSE00001791320	11019120	11019224

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 84.01.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	84.01	gold quality
sural nerve	UBERON:0015488	79.58	gold quality
primary visual cortex	UBERON:0002436	68.98	gold quality
liver	UBERON:0002107	68.67	gold quality
caudate nucleus	UBERON:0001873	67.27	gold quality
putamen	UBERON:0001874	66.65	gold quality
prefrontal cortex	UBERON:0000451	66.52	gold quality
Ammon’s horn	UBERON:0001954	66.48	gold quality
frontal cortex	UBERON:0001870	66.46	gold quality
right frontal lobe	UBERON:0002810	66.45	gold quality
right coronary artery	UBERON:0001625	66.28	gold quality
cortical plate	UBERON:0005343	65.90	gold quality
substantia nigra	UBERON:0002038	65.83	gold quality
ganglionic eminence	UBERON:0004023	65.83	gold quality
nucleus accumbens	UBERON:0001882	65.56	gold quality
ventricular zone	UBERON:0003053	65.56	gold quality
amygdala	UBERON:0001876	65.41	gold quality
superior frontal gyrus	UBERON:0002661	65.37	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.12	gold quality
cerebral cortex	UBERON:0000956	65.00	gold quality
apex of heart	UBERON:0002098	64.58	gold quality
skeletal muscle tissue	UBERON:0001134	64.55	gold quality
anterior cingulate cortex	UBERON:0009835	64.50	gold quality
hypothalamus	UBERON:0001898	63.96	gold quality
right lobe of liver	UBERON:0001114	63.35	gold quality
brain	UBERON:0000955	63.02	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.58	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.35	gold quality
popliteal artery	UBERON:0002250	61.53	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	45.68
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.