SLC9A3-AS1

Summary

SLC9A3-AS1 (SLC9A3 antisense RNA 1, HGNC:40550) is a long non-coding RNA gene on chromosome 5p15.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40550
Approved symbol	SLC9A3-AS1
Name	SLC9A3 antisense RNA 1
Location	5p15.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	UC011CLY.2
Ensembl gene	ENSG00000225138
Ensembl biotype	lncRNA
Entrez	100288152
RNAcentral	URS00007E3DFD — lncRNA, 1782 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 10 lncRNA, 3 retained_intron

ENST00000534918, ENST00000606074, ENST00000606107, ENST00000606288, ENST00000606319, ENST00000607005, ENST00000607286, ENST00000655313, ENST00000658086, ENST00000658225, ENST00000667376, ENST00000667998, ENST00000668009

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000534918 — 1 exons

Exon	Start	End
ENSE00002240290	478123	480884

Expression profiles

Bgee: expression breadth ubiquitous, 215 present calls, max score 99.40.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.3207 / max 302.8948, expressed in 1528 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55491	7.3207	1528

Top tissues by expression

253 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	99.40	gold quality
right testis	UBERON:0004534	98.68	gold quality
lower esophagus mucosa	UBERON:0035834	98.49	gold quality
left testis	UBERON:0004533	98.48	gold quality
metanephros cortex	UBERON:0010533	98.12	gold quality
mucosa of transverse colon	UBERON:0004991	98.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	97.57	gold quality
adenohypophysis	UBERON:0002196	97.24	gold quality
esophagus mucosa	UBERON:0002469	97.15	gold quality
skin of abdomen	UBERON:0001416	97.11	gold quality
cerebellar hemisphere	UBERON:0002245	96.66	gold quality
cerebellar cortex	UBERON:0002129	96.42	gold quality
tibial nerve	UBERON:0001323	96.02	gold quality
vagina	UBERON:0000996	95.95	gold quality
left ovary	UBERON:0002119	95.94	gold quality
pituitary gland	UBERON:0000007	95.89	gold quality
left uterine tube	UBERON:0001303	95.75	gold quality
skin of leg	UBERON:0001511	95.69	gold quality
testis	UBERON:0000473	95.68	gold quality
sural nerve	UBERON:0015488	95.65	gold quality
right frontal lobe	UBERON:0002810	95.62	gold quality
right ovary	UBERON:0002118	95.07	gold quality
left lobe of thyroid gland	UBERON:0001120	95.05	gold quality
cerebellum	UBERON:0002037	95.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	94.99	gold quality
minor salivary gland	UBERON:0001830	94.97	gold quality
right lobe of thyroid gland	UBERON:0001119	94.63	gold quality
gall bladder	UBERON:0002110	94.51	gold quality
upper arm skin	UBERON:0004263	94.26	silver quality
oviduct epithelium	UBERON:0004804	94.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.96

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA SLC9A3AS1 increases E2F6 expression by sponging microRNA4865p and thus facilitates the oncogenesis of nasopharyngeal carcinoma. (PMID:34165171)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.