SLC9A3-OT1

Summary

SLC9A3-OT1 (SLC9A3 3’ UTR overlapping transcript 1, HGNC:24524) is a long non-coding RNA gene on chromosome 5p15.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:24524
Approved symbol	SLC9A3-OT1
Name	SLC9A3 3’ UTR overlapping transcript 1
Location	5p15.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	PP7080
Ensembl gene	ENSG00000188242
Ensembl biotype	lncRNA
Entrez	25845
RNAcentral	URS000075B559 — lncRNA, 1760 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000342584, ENST00000502511, ENST00000510604, ENST00000510714

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000342584 — 2 exons

Exon	Start	End
ENSE00001364331	470510	471965
ENSE00001371950	472679	473098

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 98.87.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 12.3573 / max 92.6380, expressed in 1721 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
60710	7.8302	1672
60708	3.2386	1253
60709	1.2886	675

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of transverse colon	UBERON:0004991	98.87	gold quality
adult mammalian kidney	UBERON:0000082	91.39	gold quality
gall bladder	UBERON:0002110	91.18	gold quality
metanephros cortex	UBERON:0010533	90.48	gold quality
fundus of stomach	UBERON:0001160	90.02	gold quality
duodenum	UBERON:0002114	89.95	gold quality
kidney	UBERON:0002113	89.75	gold quality
body of stomach	UBERON:0001161	89.71	gold quality
transverse colon	UBERON:0001157	88.81	gold quality
stomach	UBERON:0000945	88.03	gold quality
cortex of kidney	UBERON:0001225	87.46	gold quality
adenohypophysis	UBERON:0002196	87.40	gold quality
small intestine	UBERON:0002108	87.36	gold quality
small intestine Peyer’s patch	UBERON:0003454	87.36	gold quality
pituitary gland	UBERON:0000007	87.04	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.91	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	86.48	gold quality
intestine	UBERON:0000160	85.26	gold quality
lower esophagus mucosa	UBERON:0035834	84.95	gold quality
colon	UBERON:0001155	84.76	gold quality
gastrocnemius	UBERON:0001388	84.28	gold quality
muscle of leg	UBERON:0001383	84.01	gold quality
tibial nerve	UBERON:0001323	83.41	gold quality
skeletal muscle tissue	UBERON:0001134	83.37	gold quality
hindlimb stylopod muscle	UBERON:0004252	82.99	gold quality
muscle tissue	UBERON:0002385	82.39	gold quality
skin of abdomen	UBERON:0001416	81.70	gold quality
zone of skin	UBERON:0000014	81.34	gold quality
body of pancreas	UBERON:0001150	81.22	gold quality
right lobe of thyroid gland	UBERON:0001119	81.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.41

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• PP7080 expedites the proliferation and migration of lung adenocarcinoma cells via sponging miR-670-3p and regulating UHRF1BP1. (PMID:33844396)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.