SLIRP-OT1

Summary

SLIRP-OT1 (SLIRP overlapping transcript 1, HGNC:26385) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26385
Approved symbol	SLIRP-OT1
Name	SLIRP overlapping transcript 1
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ25976
Ensembl gene	ENSG00000197734
Ensembl biotype	lncRNA
Entrez	283579
RNAcentral	URS0000E60A38 — lncRNA, 708 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000556047, ENST00000557011, ENST00000650032

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556047 — 3 exons

Exon	Start	End
ENSE00002485564	77768452	77768523
ENSE00002509435	77760974	77761116
ENSE00003657728	77769398	77769728

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 83.14.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3470 / max 64.6372, expressed in 419 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
140789	0.7155	333
140788	0.6314	114

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.14	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.87	gold quality
bone marrow cell	CL:0002092	71.38	silver quality
ganglionic eminence	UBERON:0004023	66.13	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.70	gold quality
stromal cell of endometrium	CL:0002255	61.54	gold quality
skeletal muscle tissue	UBERON:0001134	61.18	gold quality
bone marrow	UBERON:0002371	59.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.98	gold quality
prefrontal cortex	UBERON:0000451	57.73	gold quality
mucosa of transverse colon	UBERON:0004991	57.62	gold quality
right coronary artery	UBERON:0001625	56.73	gold quality
lymph node	UBERON:0000029	56.71	gold quality
leukocyte	CL:0000738	56.66	gold quality
lower esophagus mucosa	UBERON:0035834	56.30	gold quality
monocyte	CL:0000576	55.92	gold quality
muscle of leg	UBERON:0001383	55.87	gold quality
blood	UBERON:0000178	55.58	gold quality
granulocyte	CL:0000094	55.57	gold quality
gastrocnemius	UBERON:0001388	55.48	gold quality
duodenum	UBERON:0002114	55.09	gold quality
islet of Langerhans	UBERON:0000006	55.02	gold quality
vermiform appendix	UBERON:0001154	54.86	gold quality
amygdala	UBERON:0001876	54.78	gold quality
Ammon’s horn	UBERON:0001954	54.62	gold quality
placenta	UBERON:0001987	54.52	gold quality
primary visual cortex	UBERON:0002436	54.38	gold quality
superior frontal gyrus	UBERON:0002661	54.17	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.03	gold quality
liver	UBERON:0002107	53.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.