SLIT3-AS1

Summary

SLIT3-AS1 (SLIT3 antisense RNA 1, HGNC:40553) is a long non-coding RNA gene on chromosome 5q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40553
Approved symbol	SLIT3-AS1
Name	SLIT3 antisense RNA 1
Location	5q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248222
Ensembl biotype	lncRNA
Entrez	728095
RNAcentral	URS000075C609 — lncRNA, 869 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000504527, ENST00000507092, ENST00000507304, ENST00000508470, ENST00000508547, ENST00000508600, ENST00000509170, ENST00000511447, ENST00000512417, ENST00000513790, ENST00000718526

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504527 — 3 exons

Exon	Start	End
ENSE00002027112	169013248	169013384
ENSE00002033752	169018393	169018702
ENSE00002045222	169017832	169017941

Expression profiles

Bgee: expression breadth ubiquitous, 137 present calls, max score 85.50.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0301 / max 23.0053, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
60085	0.0301	6

Top tissues by expression

226 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	85.50	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.13	gold quality
right testis	UBERON:0004534	84.11	gold quality
testis	UBERON:0000473	81.76	gold quality
sperm	CL:0000019	81.68	silver quality
bone marrow cell	CL:0002092	75.66	silver quality
colonic epithelium	UBERON:0000397	75.62	gold quality
calcaneal tendon	UBERON:0003701	74.89	gold quality
sural nerve	UBERON:0015488	73.66	gold quality
adrenal tissue	UBERON:0018303	67.65	gold quality
tendon	UBERON:0000043	63.86	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.41	gold quality
tonsil	UBERON:0002372	57.82	gold quality
gall bladder	UBERON:0002110	54.94	gold quality
cerebellar cortex	UBERON:0002129	54.52	gold quality
cerebellar hemisphere	UBERON:0002245	54.30	gold quality
cerebellum	UBERON:0002037	53.62	gold quality
muscle of leg	UBERON:0001383	53.46	gold quality
apex of heart	UBERON:0002098	52.86	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.55	gold quality
adrenal gland	UBERON:0002369	52.35	gold quality
urinary bladder	UBERON:0001255	52.23	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.94	gold quality
popliteal artery	UBERON:0002250	51.34	gold quality
monocyte	CL:0000576	51.29	silver quality
tibial artery	UBERON:0007610	51.23	gold quality
corpus callosum	UBERON:0002336	50.77	gold quality
stomach	UBERON:0000945	50.67	gold quality
uterine cervix	UBERON:0000002	50.62	silver quality
prefrontal cortex	UBERON:0000451	50.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.