SMAD1-AS1

Summary

SMAD1-AS1 (SMAD1 antisense RNA 1, HGNC:49379) is a long non-coding RNA gene on chromosome 4q31.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49379
Approved symbol	SMAD1-AS1
Name	SMAD1 antisense RNA 1
Location	4q31.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000513542
Ensembl gene	ENSG00000250902
Ensembl biotype	lncRNA
Entrez	104326058
RNAcentral	URS00007E4F68 — lncRNA, 594 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000513542

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513542 — 2 exons

Exon	Start	End
ENSE00002035825	145514615	145514990
ENSE00002038737	145517014	145517118

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 91.10.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	91.10	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.84	gold quality
placenta	UBERON:0001987	76.04	gold quality
urinary bladder	UBERON:0001255	74.25	gold quality
stromal cell of endometrium	CL:0002255	72.56	gold quality
tonsil	UBERON:0002372	68.28	gold quality
ganglionic eminence	UBERON:0004023	67.73	gold quality
monocyte	CL:0000576	66.23	gold quality
liver	UBERON:0002107	66.04	gold quality
bone marrow cell	CL:0002092	64.59	silver quality
hindlimb stylopod muscle	UBERON:0004252	62.36	gold quality
prefrontal cortex	UBERON:0000451	62.29	gold quality
skeletal muscle tissue	UBERON:0001134	61.70	silver quality
kidney	UBERON:0002113	61.13	gold quality
islet of Langerhans	UBERON:0000006	59.40	gold quality
gall bladder	UBERON:0002110	58.85	gold quality
myometrium	UBERON:0001296	58.76	gold quality
primary visual cortex	UBERON:0002436	58.31	gold quality
stomach	UBERON:0000945	57.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.60	gold quality
thoracic mammary gland	UBERON:0005200	57.46	gold quality
blood	UBERON:0000178	56.98	gold quality
heart	UBERON:0000948	56.19	gold quality
fundus of stomach	UBERON:0001160	55.87	gold quality
heart left ventricle	UBERON:0002084	55.18	gold quality
uterine cervix	UBERON:0000002	54.07	silver quality
gastrocnemius	UBERON:0001388	53.83	gold quality
endometrium	UBERON:0001295	53.54	gold quality
lung	UBERON:0002048	52.97	gold quality
adrenal tissue	UBERON:0018303	52.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.