SMCR5

Summary

SMCR5 (Smith-Magenis syndrome chromosome region, candidate 5, HGNC:17918) is a long non-coding RNA gene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:17918
Approved symbol	SMCR5
Name	Smith-Magenis syndrome chromosome region, candidate 5
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00034
Ensembl gene	ENSG00000226746
Ensembl biotype	lncRNA
Entrez	140771
RNAcentral	URS000040501C — lncRNA, 2844 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000543475

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000543475 — 1 exons

Exon	Start	End
ENSE00002316301	17776686	17779529

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 82.33.

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	82.33	gold quality
buccal mucosa cell	CL:0002336	80.95	gold quality
cerebellar vermis	UBERON:0004720	64.97	silver quality
tendon of biceps brachii	UBERON:0008188	63.20	gold quality
colonic epithelium	UBERON:0000397	59.34	silver quality
myocardium	UBERON:0002349	57.99	gold quality
tonsil	UBERON:0002372	56.25	silver quality
cartilage tissue	UBERON:0002418	54.91	gold quality
nipple	UBERON:0002030	54.50	gold quality
pericardium	UBERON:0002407	54.17	silver quality
ventral tegmental area	UBERON:0002691	53.10	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	52.96	gold quality
lymph node	UBERON:0000029	52.76	gold quality
sperm	CL:0000019	52.38	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.16	gold quality
urethra	UBERON:0000057	52.06	gold quality
pylorus	UBERON:0001166	52.01	gold quality
cardia of stomach	UBERON:0001162	51.82	gold quality
layer of synovial tissue	UBERON:0007616	51.80	gold quality
saphenous vein	UBERON:0007318	51.78	gold quality
prefrontal cortex	UBERON:0000451	51.73	gold quality
decidua	UBERON:0002450	51.68	gold quality
trachea	UBERON:0003126	51.64	gold quality
superior vestibular nucleus	UBERON:0007227	51.61	gold quality
biceps brachii	UBERON:0001507	51.57	gold quality
cerebellar cortex	UBERON:0002129	51.57	gold quality
coronary artery	UBERON:0001621	51.53	gold quality
synovial joint	UBERON:0002217	51.52	gold quality
dorsal root ganglion	UBERON:0000044	51.48	gold quality
cerebellar hemisphere	UBERON:0002245	51.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.