SMG1-DT

Summary

SMG1-DT (SMG1 divergent transcript, HGNC:55394) is a long non-coding RNA gene on chromosome 16p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55394
Approved symbol	SMG1-DT
Name	SMG1 divergent transcript
Location	16p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260352
Ensembl biotype	lncRNA
Entrez	107984844
RNAcentral	URS0002A6BB8C — lncRNA, 1112 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000565782, ENST00000810124, ENST00000810125

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000565782 — 2 exons

Exon	Start	End
ENSE00004206662	18936856	18937401
ENSE00004206663	18926572	18927137

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 88.18.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.89	silver quality
skeletal muscle tissue	UBERON:0001134	75.33	gold quality
mucosa of transverse colon	UBERON:0004991	69.41	gold quality
sural nerve	UBERON:0015488	65.61	silver quality
lower esophagus mucosa	UBERON:0035834	62.07	gold quality
transverse colon	UBERON:0001157	61.36	gold quality
rectum	UBERON:0001052	61.06	gold quality
bone marrow	UBERON:0002371	61.06	gold quality
apex of heart	UBERON:0002098	60.98	gold quality
liver	UBERON:0002107	60.88	gold quality
duodenum	UBERON:0002114	60.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.11	gold quality
right lobe of liver	UBERON:0001114	60.09	gold quality
kidney	UBERON:0002113	57.76	gold quality
adult mammalian kidney	UBERON:0000082	57.56	gold quality
placenta	UBERON:0001987	57.53	gold quality
islet of Langerhans	UBERON:0000006	57.35	gold quality
lymph node	UBERON:0000029	56.92	gold quality
cortex of kidney	UBERON:0001225	56.72	gold quality
colon	UBERON:0001155	56.49	gold quality
blood	UBERON:0000178	56.42	gold quality
muscle of leg	UBERON:0001383	56.22	gold quality
intestine	UBERON:0000160	56.07	gold quality
heart left ventricle	UBERON:0002084	56.06	gold quality
gastrocnemius	UBERON:0001388	56.05	gold quality
leukocyte	CL:0000738	55.42	gold quality
monocyte	CL:0000576	55.35	gold quality
metanephros cortex	UBERON:0010533	55.29	gold quality
left lobe of thyroid gland	UBERON:0001120	55.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.