SMG6-AS1

Summary

SMG6-AS1 (SMG6 antisense RNA 1, HGNC:58200) is a long non-coding RNA gene on chromosome 17p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58200
Approved symbol	SMG6-AS1
Name	SMG6 antisense RNA 1
Location	17p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000262810
Ensembl biotype	lncRNA
Entrez	139281646
RNAcentral	URS000047FDC0 — lncRNA, 528 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000571815

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000571815 — 2 exons

Exon	Start	End
ENSE00002638250	2101122	2101560
ENSE00002680530	2089681	2089769

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 83.36.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.36	gold quality
colonic epithelium	UBERON:0000397	71.83	gold quality
bone marrow cell	CL:0002092	66.02	silver quality
skeletal muscle tissue	UBERON:0001134	65.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.67	gold quality
bone marrow	UBERON:0002371	63.38	gold quality
calcaneal tendon	UBERON:0003701	60.73	gold quality
tonsil	UBERON:0002372	59.69	gold quality
monocyte	CL:0000576	58.41	gold quality
lymph node	UBERON:0000029	56.63	gold quality
granulocyte	CL:0000094	56.41	gold quality
placenta	UBERON:0001987	55.96	gold quality
liver	UBERON:0002107	55.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.53	gold quality
islet of Langerhans	UBERON:0000006	55.49	gold quality
duodenum	UBERON:0002114	54.80	gold quality
blood	UBERON:0000178	54.75	gold quality
gall bladder	UBERON:0002110	54.50	gold quality
vermiform appendix	UBERON:0001154	54.28	gold quality
prefrontal cortex	UBERON:0000451	53.49	gold quality
superior frontal gyrus	UBERON:0002661	53.10	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.96	gold quality
urinary bladder	UBERON:0001255	52.34	gold quality
muscle of leg	UBERON:0001383	51.96	gold quality
kidney	UBERON:0002113	51.55	gold quality
gastrocnemius	UBERON:0001388	50.86	gold quality
uterine cervix	UBERON:0000002	50.81	gold quality
smooth muscle tissue	UBERON:0001135	50.79	gold quality
adult mammalian kidney	UBERON:0000082	50.61	gold quality
lower esophagus mucosa	UBERON:0035834	49.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.