SMIM14-DT

Summary

SMIM14-DT (SMIM14 divergent transcript, HGNC:53455) is a long non-coding RNA gene on chromosome 4p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53455
Approved symbol	SMIM14-DT
Name	SMIM14 divergent transcript
Location	4p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255458
Ensembl biotype	lncRNA
Entrez	105374419
RNAcentral	URS00026A213E — lncRNA, 3074 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000526807, ENST00000529314, ENST00000532680, ENST00000657228, ENST00000659162, ENST00000666863, ENST00000667934, ENST00000693190, ENST00000706646, ENST00000719138, ENST00000719139, ENST00000719140, ENST00000719141, ENST00000719142, ENST00000719143, ENST00000719144, ENST00000719145, ENST00000719146, ENST00000719147, ENST00000719148, ENST00000719149, ENST00000719150, ENST00000719151

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526807 — 5 exons

Exon	Start	End
ENSE00002168634	39666123	39666645
ENSE00003848634	39641690	39641792
ENSE00003996402	39650377	39650454
ENSE00004036559	39639115	39639294
ENSE00004036563	39651266	39653465

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 86.01.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4713 / max 14.3536, expressed in 229 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
47383	0.4713	229

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	86.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.78	gold quality
right testis	UBERON:0004534	75.02	gold quality
left testis	UBERON:0004533	74.36	gold quality
testis	UBERON:0000473	73.05	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.41	gold quality
bone marrow cell	CL:0002092	68.30	silver quality
cortical plate	UBERON:0005343	66.25	gold quality
ganglionic eminence	UBERON:0004023	65.84	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	64.40	gold quality
ventricular zone	UBERON:0003053	63.69	gold quality
right lobe of liver	UBERON:0001114	62.51	gold quality
spinal cord	UBERON:0002240	62.20	gold quality
oviduct epithelium	UBERON:0004804	61.41	gold quality
monocyte	CL:0000576	61.28	gold quality
granulocyte	CL:0000094	61.19	gold quality
adenohypophysis	UBERON:0002196	60.10	gold quality
islet of Langerhans	UBERON:0000006	59.63	gold quality
right adrenal gland cortex	UBERON:0035827	59.33	gold quality
right adrenal gland	UBERON:0001233	59.28	gold quality
pituitary gland	UBERON:0000007	59.22	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.57	gold quality
metanephros cortex	UBERON:0010533	58.35	gold quality
pancreas	UBERON:0001264	57.76	gold quality
amygdala	UBERON:0001876	57.71	gold quality
left adrenal gland	UBERON:0001234	57.68	gold quality
body of pancreas	UBERON:0001150	57.56	gold quality
left lobe of thyroid gland	UBERON:0001120	57.50	gold quality
right lobe of thyroid gland	UBERON:0001119	57.49	gold quality
hypothalamus	UBERON:0001898	57.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.