SMIM15-AS1

Summary

SMIM15-AS1 (SMIM15 antisense RNA 1, HGNC:41293) is a long non-coding RNA gene on chromosome 5q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41293
Approved symbol	SMIM15-AS1
Name	SMIM15 antisense RNA 1
Location	5q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251279
Ensembl biotype	lncRNA
Entrez	101928630
RNAcentral	URS000075F0C2 — lncRNA, 590 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000506902, ENST00000687774, ENST00000693134, ENST00000821105, ENST00000821106, ENST00000821107, ENST00000821108, ENST00000821109, ENST00000821110, ENST00000821111, ENST00000821112, ENST00000821113, ENST00000821114, ENST00000821115, ENST00000821116, ENST00000821117

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506902 — 4 exons

Exon	Start	End
ENSE00002037266	61180352	61180438
ENSE00002072605	61179704	61179827
ENSE00004227590	61162070	61162526
ENSE00004227595	61231913	61232254

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 83.57.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5280 / max 22.1598, expressed in 303 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
56617	0.5280	303

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.57	gold quality
sural nerve	UBERON:0015488	77.39	gold quality
bone marrow cell	CL:0002092	67.14	silver quality
ventricular zone	UBERON:0003053	66.30	gold quality
ganglionic eminence	UBERON:0004023	64.01	gold quality
right uterine tube	UBERON:0001302	61.94	gold quality
stromal cell of endometrium	CL:0002255	61.53	gold quality
cortical plate	UBERON:0005343	61.53	gold quality
skeletal muscle tissue	UBERON:0001134	60.84	gold quality
prefrontal cortex	UBERON:0000451	59.80	gold quality
monocyte	CL:0000576	59.45	gold quality
leukocyte	CL:0000738	58.96	gold quality
bone marrow	UBERON:0002371	58.54	gold quality
calcaneal tendon	UBERON:0003701	58.47	gold quality
liver	UBERON:0002107	58.16	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.81	gold quality
superior frontal gyrus	UBERON:0002661	57.15	gold quality
placenta	UBERON:0001987	56.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.14	gold quality
frontal cortex	UBERON:0001870	54.97	gold quality
lower esophagus mucosa	UBERON:0035834	54.55	gold quality
tonsil	UBERON:0002372	54.22	silver quality
muscle of leg	UBERON:0001383	52.51	gold quality
endometrium	UBERON:0001295	52.49	gold quality
kidney	UBERON:0002113	52.28	gold quality
gall bladder	UBERON:0002110	52.20	gold quality
gastrocnemius	UBERON:0001388	51.96	gold quality
testis	UBERON:0000473	51.88	gold quality
islet of Langerhans	UBERON:0000006	51.76	gold quality
granulocyte	CL:0000094	51.69	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	31.04
E-ANND-3	no	1.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.