SMN2-AS1

Summary

SMN2-AS1 (SMN2 antisense RNA 1, HGNC:53121) is a long non-coding RNA gene.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53121
Approved symbol	SMN2-AS1
Name	SMN2 antisense RNA 1
Locus type	RNA, long non-coding
Status	Approved
Aliases	SMN-AS1
Ensembl gene	ENSG00000285151
Ensembl biotype	lncRNA
Entrez	139198554
RNAcentral	URS0000D6429B — lncRNA, 1597 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000643472

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000643472 — 1 exons

Exon	Start	End
ENSE00003819795	70055820	70057416

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 68.74.

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	68.74	silver quality
ventricular zone	UBERON:0003053	61.76	gold quality
bone marrow	UBERON:0002371	58.33	silver quality
ganglionic eminence	UBERON:0004023	57.99	silver quality
cortical plate	UBERON:0005343	57.67	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.46	gold quality
skeletal muscle tissue	UBERON:0001134	56.24	silver quality
tonsil	UBERON:0002372	54.61	silver quality
stromal cell of endometrium	CL:0002255	53.60	silver quality
monocyte	CL:0000576	53.47	silver quality
blood	UBERON:0000178	52.44	silver quality
calcaneal tendon	UBERON:0003701	51.89	silver quality
uterine cervix	UBERON:0000002	50.51	silver quality
urinary bladder	UBERON:0001255	48.90	silver quality
lymph node	UBERON:0000029	48.60	silver quality
liver	UBERON:0002107	48.47	silver quality
superior frontal gyrus	UBERON:0002661	48.47	silver quality
cortex of kidney	UBERON:0001225	48.22	silver quality
adrenal tissue	UBERON:0018303	48.15	silver quality
kidney	UBERON:0002113	47.65	silver quality
muscle of leg	UBERON:0001383	47.26	silver quality
islet of Langerhans	UBERON:0000006	47.22	silver quality
prefrontal cortex	UBERON:0000451	46.51	silver quality
corpus callosum	UBERON:0002336	45.40	silver quality
primary visual cortex	UBERON:0002436	45.12	silver quality
right lobe of liver	UBERON:0001114	45.01	silver quality
gastrocnemius	UBERON:0001388	44.86	silver quality
hindlimb stylopod muscle	UBERON:0004252	44.22	silver quality
endometrium	UBERON:0001295	44.10	silver quality
pancreas	UBERON:0001264	44.06	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): SMN1-AS1 (ENSG00000285204)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.