SMYD3-AS1

Summary

SMYD3-AS1 (SMYD3 antisense RNA 1, HGNC:40708) is a long non-coding RNA gene on chromosome 1q44.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40708
Approved symbol	SMYD3-AS1
Name	SMYD3 antisense RNA 1
Location	1q44
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226876
Ensembl biotype	lncRNA
Entrez	101928089
RNAcentral	URS00026A267F — lncRNA, 584 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000443763, ENST00000651181

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443763 — 4 exons

Exon	Start	End
ENSE00001656910	246111331	246111529
ENSE00001759482	246108626	246108717
ENSE00001795853	246109782	246109893
ENSE00004172337	246113689	246113869

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 86.95.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.95	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.06	gold quality
sural nerve	UBERON:0015488	81.01	gold quality
corpus callosum	UBERON:0002336	78.67	gold quality
skeletal muscle tissue	UBERON:0001134	70.03	silver quality
bone marrow cell	CL:0002092	68.77	silver quality
calcaneal tendon	UBERON:0003701	68.15	gold quality
spinal cord	UBERON:0002240	67.45	silver quality
colonic epithelium	UBERON:0000397	65.61	silver quality
cerebellar vermis	UBERON:0004720	65.23	gold quality
adrenal tissue	UBERON:0018303	64.57	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
tonsil	UBERON:0002372	63.70	silver quality
liver	UBERON:0002107	62.90	gold quality
thymus	UBERON:0002370	61.45	silver quality
lymph node	UBERON:0000029	59.74	gold quality
urinary bladder	UBERON:0001255	59.57	silver quality
bone marrow	UBERON:0002371	59.40	gold quality
blood	UBERON:0000178	59.31	gold quality
right testis	UBERON:0004534	57.64	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.36	gold quality
testis	UBERON:0000473	55.83	gold quality
kidney	UBERON:0002113	55.79	gold quality
left testis	UBERON:0004533	55.31	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.98	gold quality
islet of Langerhans	UBERON:0000006	54.18	gold quality
monocyte	CL:0000576	53.74	gold quality
endometrium	UBERON:0001295	53.48	gold quality
adult mammalian kidney	UBERON:0000082	52.76	gold quality
stomach	UBERON:0000945	51.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.