SMYD3-IT1

Summary

SMYD3-IT1 (SMYD3 intronic transcript 1, HGNC:41406) is a long non-coding RNA gene on chromosome 1q44.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41406
Approved symbol	SMYD3-IT1
Name	SMYD3 intronic transcript 1
Location	1q44
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230184
Ensembl biotype	lncRNA
Entrez	106478975
RNAcentral	URS0002853A92 — lncRNA, 4887 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000426929

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426929 — 2 exons

Exon	Start	End
ENSE00001592719	246322284	246322438
ENSE00001674281	246321663	246321868

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 86.53.

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	86.53	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.53	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.92	gold quality
buccal mucosa cell	CL:0002336	76.91	silver quality
ventricular zone	UBERON:0003053	71.01	gold quality
bone marrow cell	CL:0002092	68.47	gold quality
adrenal tissue	UBERON:0018303	61.11	gold quality
islet of Langerhans	UBERON:0000006	60.33	gold quality
apex of heart	UBERON:0002098	59.80	gold quality
calcaneal tendon	UBERON:0003701	58.03	gold quality
lower lobe of lung	UBERON:0008949	57.94	silver quality
tonsil	UBERON:0002372	57.47	gold quality
corpus callosum	UBERON:0002336	55.86	gold quality
monocyte	CL:0000576	55.84	gold quality
prefrontal cortex	UBERON:0000451	55.34	gold quality
muscle of leg	UBERON:0001383	54.74	gold quality
uterine cervix	UBERON:0000002	54.60	gold quality
ectocervix	UBERON:0012249	54.27	gold quality
pancreas	UBERON:0001264	54.14	gold quality
gastrocnemius	UBERON:0001388	53.95	gold quality
body of pancreas	UBERON:0001150	51.92	gold quality
blood	UBERON:0000178	51.02	gold quality
tibial artery	UBERON:0007610	50.98	gold quality
popliteal artery	UBERON:0002250	50.90	gold quality
medial globus pallidus	UBERON:0002477	50.75	gold quality
mucosa of stomach	UBERON:0001199	50.64	gold quality
lower esophagus muscularis layer	UBERON:0035833	50.40	gold quality
lower esophagus	UBERON:0013473	50.37	gold quality
right adrenal gland cortex	UBERON:0035827	50.21	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	50.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.